93000-10-3Relevant articles and documents
Preparation method of fondaparinux sodium monosaccharide intermediate
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Paragraph 0045; 0046; 0049-0050; 0055; 0058-0059; 0064; 0067, (2019/03/06)
The invention discloses a preparation method of a fondaparinux sodium monosaccharide intermediate. The preparation method includes using methyl glucose protected by C4 and C6 positions as a raw material to obtain methyl 3-O-benzyl-4,6-O-benzylidene-2-(ben
Adverse effects of alkali and acid on the anticoagulant potency of heparin, evaluated with methyl 2-deoxy-2-sulfamino-α-D-glucopyranoside 3-sulfate as a model compound
Liu, Zhengchun,Perlin, Arthur S.
, p. 29 - 36 (2007/10/02)
A variety of chemical modifications can induce a reduction in the anticoagulant activity of heparin.Among such modifications are the removal in alkaline solution of the 2-O-sulfonate group of α-L-idopyranosyluronic acid 2-sulfate residues (1) and, in a we