930088-04-3Relevant articles and documents
Synthesis and anti-platelet activity of novel arylsulfonate-acylhydrazone derivatives, designed as antithrombotic candidates
Lima, Lidia M.,Frattani, Flavia S.,dos Santos, Jean L.,Castro, Helena C.,Fraga, Carlos Alberto M.,Zingali, Russolina B.,Barreiro, Eliezer J.
, p. 348 - 356 (2008)
In this work, we describe a new class of promising anti-platelet drug candidates with significant antithrombotic activity in vivo. This new series of compounds was structurally planned by modification of known thrombin inhibitors based on the use of acylh