930101-83-0Relevant articles and documents
Design, synthesis and cytotoxic evaluation of a library of oxadiazole-containing hybrids
Barrionuevo, Elizabeth,Bellizzi, Yanina,Blank, Viviana C.,Boggián, Dora B.,Camacho, Cristián M.,Mata, Ernesto G.,Pizzio, Marianela G.,Roces, David L.,Roguin, Leonor P.
, p. 29741 - 29751 (2021/10/07)
The development of hybrid compounds led to the discovery of new pharmacologically active agents for some of the most critical diseases, including cancer. Herein, we describe a new series of oxadiazole-containing structures designed by a molecular hybridiz
IAP ANTAGONISTS
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Paragraph 00265, (2014/01/09)
There are disclosed compounds that modulate the activity of inhibitors of apoptosis (IAPs), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.
Synthesis of 1,2,4-oxadiazole-linked orthogonally urethane-protected dipeptide mimetics
Sureshbabu, Vommina V.,Hemantha, Hosahalli P.,Naik, Shankar A.
, p. 5133 - 5136 (2008/12/20)
The synthesis of a new class of 1,2,4-oxadiazole-linked orthogonally urethane-protected dipeptide mimetics is described. The protocol employs a reaction between an N-protected amino acyl fluoride and an amino acid-derived amidoxime. All the three commonly