931-23-7

Basic information

• Product Name: 5-hydroxy-3-Methyl-2(5H)-furanone
• Synonyms: 5-hydroxy-3-Methyl-2(5H)-furanone;2(5H)-Furanone, 5-hydroxy-3-methyl-;2-hydroxy-4-methyl-2H-furan-5-one
• CAS NO: 931-23-7
• Molecular Formula: C₅H₆O₃
• Molecular Weight: 114.09934
• Mol File: 931-23-7.mol
• Article Data: 3

Chemical Properties

• Melting Point: 72-73 °C
• Boiling Point: 90 °C(Press: 0.1 Torr)
• Appearance: /
• Density: 1.349±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 10.03±0.40(Predicted)
• CAS DataBase Reference: 5-hydroxy-3-Methyl-2(5H)-furanone(CAS DataBase Reference)
• NIST Chemistry Reference: 5-hydroxy-3-Methyl-2(5H)-furanone(931-23-7)
• EPA Substance Registry System: 5-hydroxy-3-Methyl-2(5H)-furanone(931-23-7)

Safety Data

• Hazardous Substances Data: 931-23-7(Hazardous Substances Data)

Usage

Description

5-Hydroxy-3-Methyl-2(5H)-furanone is a heterocyclic organic compound with a furan ring structure, featuring a hydroxyl group and a methyl group as substituents. It is known for its unique chemical properties and potential applications in various fields.

Uses

Used in Chemical Synthesis:
5-Hydroxy-3-Methyl-2(5H)-furanone is used as a reactant/reagent for synthetic preparation, specifically for the enantioselective preparation of hydroxy-GR24 stereoisomers via contra-biomimetic nucleophilic cyclization. This application is significant in the field of organic chemistry, where the synthesis of specific stereoisomers is crucial for the development of pharmaceuticals and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 5-Hydroxy-3-Methyl-2(5H)-furanone is used as a key intermediate in the synthesis of various drug molecules. Its unique structure and reactivity make it a valuable building block for the development of new medications with improved efficacy and selectivity.
Used in Flavor and Fragrance Industry:
5-Hydroxy-3-Methyl-2(5H)-furanone is also used as a flavoring agent and a fragrance ingredient in the food and cosmetics industries. Its distinct aroma and taste profile contribute to the creation of unique and appealing sensory experiences in various products.
Used in Material Science:
In the field of material science, 5-Hydroxy-3-Methyl-2(5H)-furanone can be utilized as a component in the development of novel materials with specific properties, such as polymers with tailored characteristics for use in coatings, adhesives, or other industrial applications.
Overall, 5-Hydroxy-3-Methyl-2(5H)-furanone is a versatile compound with a wide range of applications across different industries, including chemical synthesis, pharmaceuticals, flavor and fragrance, and material science. Its unique structure and properties make it an important player in the development of innovative products and technologies.

Upstream product

• 616-02-4 citraconic acid anhydride 

Downstream Products

• 66510-25-6 2-chloro-4-methyl-2H-furan-5-one 
• 78646-58-9 C₁₀H₁₀O₅ 
• 79298-09-2 2-methyl-4-(2-oxo-2,3,3a,6a-tetrahydro-4H-cyclopentafuran-3-ylidenemethoxy)but-2-en-4-olide 
• 2938-98-9 (R)-2-methylbutane-1,4-diol 
• 120263-03-8 (3R,5R)-5-((1R,2S,5R)-2-Isopropyl-5-methyl-cyclohexyloxy)-3-methyl-dihydro-furan-2-one 
• 120329-64-8 (R)-2-methylbutane-1,4-diol dibenzoate 
• 1338600-67-1 4-methyl-5-oxo-2,5-dihydrofuran-2-yl 2-(3,4-dimethylphenyl)ethylcarbamate 
• 1338600-54-6 4-methyl-5-oxo-2,5-dihydrofuran-2-yl benzylcarbamate 
• 1338600-55-7 4-methyl-5-oxo-2,5-dihydrofuran-2-yl phenethylcarbamate 
• 1338600-56-8 4-methyl-5-oxo-2,5-dihydrofuran-2-yl methyl(phenyl)carbamate 
• 1338600-57-9 4-methyl-5-oxo-2,5-dihydrofuran-2-yl benzyl(methyl)carbamate 
• 1338600-63-7 4-methyl-5-oxo-2,5-dihydrofuran-2-yl 2-phenethyl(methyl)carbamate 
• 1338600-66-0 4-methyl-5-oxo-2,5-dihydrofuran-2-yl 2-(2,3-dimethylphenyl)ethylcarbamate 
• 1338600-62-6 4-methyl-5-oxo-2,5-dihydrofuran-2-yl phenylcarbamate 

Relevant articles and documents

Synthesis of a 13C-labelled seed-germination inhibitor (3,4,5-trimethylfuran-2(5H)-one) for the mode of action elucidation

Abstract: It has been found that the butenolide 3,4,5-trimethylfuran-2(5H)-one, isolated from plant-derived smoke, efficiently inhibits seed germination and significantly reduces the effect of the highly active germination promotor karrikinolide (KAR

Propenals substituted with a dithiane ring and processes for the preparation of these propenals

Propenals of formula: STR1 in which formula R is H or a C1 -C4 thioalkyl radical, the dithiane ring being at the cis position in relation to the aldehyde function when R is H and at the trans position when R is a thioalkyl radical. The invention also relates to two processes for the preparation of these propenals.