933452-88-1Relevant articles and documents
Diastereoselective addition of chlorotitanium enolates of N-acyl thiazolidinethione to activated imines - A novel synthesis of β-lactams
Herold-Dublin, Marike,Liotta, Dennis C.
, p. 1696 - 1699 (2007/10/03)
We report a novel methodology for preparing enantiomerically pure β-lactams, starting from nitriles in diastereomeric ratios up to 10:1. The power of the methodology was demonstrated by the efficient synthesis of the cholesterol absorption inhibitor SCH 4