935528-04-4Relevant articles and documents
Novel N-substituted indol-3-ylglyoxylamides probing the LDi and L1/L2 lipophilic regions of the benzodiazepine receptor site in search for subtype-selective ligands
Primofiore, Giampaolo,Taliani, Sabrina,Da Settimo, Federico,Marini, Anna Maria,La Motta, Concettina,Simorini, Francesca,Patrizi, Maria Paola,Sergianni, Valentina,Novellino, Ettore,Greco, Giovanni,Cosimelli, Barbara,Calderone, Vincenzo,Montali, Marina,Besnard, Fran?ois,Martini, Claudia
, p. 1627 - 1634 (2007)
Novel N-substituted indol-3-ylglyoxylamides (10-37) were synthesized and evaluated as ligands of the benzodiazepine receptor (BzR). In an effort to achieve affinity-based selectivity among BzR subtypes, these compounds were designed to probe the LDi