93612-81-8

Basic information

• Product Name: tetra-n-butylammonium 2-(hydroxymethyl)benzoate
• Synonyms: tetra-n-butylammonium 2-(hydroxymethyl)benzoate
• CAS NO: 93612-81-8
• Molecular Weight: 393.61
• Mol File: 93612-81-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: tetra-n-butylammonium 2-(hydroxymethyl)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: tetra-n-butylammonium 2-(hydroxymethyl)benzoate(93612-81-8)
• EPA Substance Registry System: tetra-n-butylammonium 2-(hydroxymethyl)benzoate(93612-81-8)

Safety Data

• Hazardous Substances Data: 93612-81-8(Hazardous Substances Data)

Upstream product

• 87-41-2 2-benzofuran-1(3H)-one 
• 2052-49-5 tetra(n-butyl)ammonium hydroxide 
• 553-86-6 benzofuran-2(3H)-one 

Downstream Products

• 801301-21-3 3'-O-[(tert-butyl)dimethylsilyl]-5'-O-{2-{{[(4-methoxytrityl)thio]oxy}methyl}benzoyl}thymidine 
• 702661-01-6 5'-O-{2-{{[(4-methoxytrityl)thio]oxy}methyl}benzoyl}thymidine 
• 850848-13-4 methyl 2,3-di-O-benzyl-4,6-di-O-[2-(prenyloxymethyl)benzoyl]-α-D-glucopyranoside 
• 850848-14-5 testosterone 2-(prenyloxymethyl)benzoate 
• 850848-11-2 methyl 2-O-benzoyl-3-O-[2-(prenyloxymethyl)benzoyl]-4,6-O-benzylidene-α-D-glucopyranoside 
• 850848-12-3 methyl 2,3,4-tri-3-O-acetyl-6-O-[2-(prenyloxymethyl)benzoyl]-α-D-glucopyranoside 
• 850848-10-1 6-O-[2-(prenyloxymethyl)benzoyl]-1,2,3,4-di-O-isopropylidene-α-D-galactopyranose 
• 850848-16-7 1,5-pentanediol 4-oxopentanoyl 2-(prenyloxymethyl)benzoyl ester 
• 850848-18-9 (S)-2-tert-butyloxycarbonylamino-3-[2-(prenyloxymethyl)benzoyloxy]propionic acid methyl ester 
• 958883-15-3 (1R,2S,5R)-menthyl 2-(prenyloxymethyl)benzoate 
• 850848-15-6 1,5-pentanediol chloroacetyl 2-(prenyloxymethyl)benzoyl ester 
• 298712-28-4 (1R,2S,5R)-5-methyl-2-(methylethyl)cyclohexyl-2-(hydroxymethyl)benzoate 
• 1026731-49-6 C₁₅H₁₉O₅Cl 
• 1026816-02-3 C₁₇H₂₃O₇N 

Relevant articles and documents

New protected protecting groups for the 5′-hydroxy group of deoxynucleosides by use of 2-(hydroxymethyl)- and 2-[(methylamino)methyl]benzoyl skeletons and oxidatively cleavable tritylthio and (4-methoxytrityl)thio groups

The new protecting groups 1a,b and 2a,b were developed for the 5′-OH group of deoxynucleosides by utilizing the unique characters of the sulfenate and sulfenamide linkage. These new protecting groups have a 2-(hydroxymethyl) benzoyl or 2-[(methylamino)met

2-(Prenyloxymethyl)benzoyl (POMB) as a new temporary protecting group for alcohols

The 2-(prenyloxymethyl)benzoyl (POMB) group was introduced in high yields to hydroxyl functions using the crystalline reagent, 2-(prenyloxymethyl)benzoic acid, in the presence of dicyclohexylcarbodiimide (DCC) and 4- dimethylaminopyridine (DMAP). 2-(Prenyloxymethyl)benzoic acid is readily available, in two steps, from phthalide in 65% overall yield. The POMB group can be cleaved, in two steps, by treatment with 2,3-dichloro-5,6-dicyanoquinone (DDQ) followed by intramolecular lactonisation of the resulting hydroxy ester induced by a catalytic amount of Yb(OTf)3·H2O. The reaction conditions are compatible with the presence of a number of protecting groups such as isopropylidene, benzyl, acetyl, chloroacetyl, benzoyl, levulinoyl, Fmoc and Boc groups.