936850-09-8 Usage
General Description
The chemical "3-Cyano-3-methyl-azetidine-1-carboxylic acid tert-butyl ester" is a compound that belongs to the class of azetidine carboxylic acid derivatives. It is used in organic synthesis as a building block for the preparation of various pharmaceutical compounds and biologically active molecules. 3-Cyano-3-methyl-azetidine-1-carboxylic acid tert-butyl ester is a tert-butyl ester, which means that it contains a tert-butyl group attached to the carboxylic acid functional group. The 3-cyano and 3-methyl substituents on the azetidine ring contribute to its specific chemical and biological properties. The compound is used in research and development for the synthesis of new drugs and materials, and its properties are of interest for potential applications in the pharmaceutical and chemical industries.
Check Digit Verification of cas no
The CAS Registry Mumber 936850-09-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,3,6,8,5 and 0 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 936850-09:
(8*9)+(7*3)+(6*6)+(5*8)+(4*5)+(3*0)+(2*0)+(1*9)=198
198 % 10 = 8
So 936850-09-8 is a valid CAS Registry Number.
936850-09-8Relevant articles and documents
An improved, gram-scale synthesis of protected 3-haloazetidines: Rapid diversified synthesis of azetidine-3-carboxylic acids
Ji, Youngran,Wojtas, Lukasz,Lopchuk, Justin M.
, p. 195 - 214 (2018/06/27)
Azetidines are increasingly important heterocycles found in a variety of natural products and pharmaceutical compounds. Protected 3-haloazetidines, widely used and versatile building blocks in medicinal chemistry, have been prepared in a one-pot, gram-scale strain-release reaction of 1-azabicyclo[1.1.0]butane from commercially available starting materials. These intermediates were subsequently used to prepare a series of high value azetidine-3-carboxylic acid derivatives including the first reported synthesis of 1-(tert-butoxy-carbonyl)-3-((trifluoromethyl)thio)azetidine-3-carboxylic acid. (Figure pressented)
Pyrrolopyrazine Kinase Inhibitors
-
, (2011/10/10)
The present invention relates to the use of novel pyrrolopyrazine derivatives of Formula I, wherein the variables n, p, q, Q, X, X′ and Y are defined as described herein, which inhibit JAK and SYK and are useful for the treatment of auto-immune and inflammatory diseases.
