93704-71-3

Basic information

• Product Name: 1H-Indole-2-carboxylic acid, 3-[(2-aminophenyl)amino]-5-methyl-, ethyl ester
• CAS NO: 93704-71-3
• Molecular Formula: C18H19N3O2
• Molecular Weight: 309.368
• Mol File: 93704-71-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1H-Indole-2-carboxylic acid, 3-[(2-aminophenyl)amino]-5-methyl-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole-2-carboxylic acid, 3-[(2-aminophenyl)amino]-5-methyl-, ethyl ester(93704-71-3)
• EPA Substance Registry System: 1H-Indole-2-carboxylic acid, 3-[(2-aminophenyl)amino]-5-methyl-, ethyl ester(93704-71-3)

Safety Data

• Hazardous Substances Data: 93704-71-3(Hazardous Substances Data)

Upstream product

• 16382-15-3 5-methyl-1H-indole-2-carboxylic acid ethyl ester 
• 93704-67-7 3-bromo-5-methyl-1H-indole-2-carboxylic acid ethyl ester 
• 95-54-5 1,2-diamino-benzene 

Relevant articles and documents

Synthesis of Substituted Indolobenzodiazepine Derivatives

Various substituted-7,12-dihydroindolobenzodiazepines (4a-e) have been prepared from the corresponding 3-aminoindoles (1a-e) through Ullmann reaction with o-chloroaniline, acylation of the resulting 3-(o-aminophenylamino)indoles (2a-e) and cyclization of amides (3a-e) with POCl3.Similar systems have also been synthesized from ethyl 3-bromoindole-2-carboxylates (6a-e).The bromo esters react with o-phenylenediamine to give ethyl 3-(o-aminophenylamino)indole-2-carboxylates (7a-e) which undergo cyclization in the presence of PPA to yield 5,6,7,12-tetrahydroindolobenzodiazepin-6-ones (8a-e).