939-16-2Relevant articles and documents
Enantioselective Synthesis of Diaryl Sulfoxides Enabled by Molecular Recognition
Burg, Finn,Buchelt, Christoph,Kreienborg, Nora M.,Merten, Christian,Bach, Thorsten
, p. 1829 - 1834 (2021/03/08)
The enantioselective sulfoxidation of diaryl-type sulfides was accomplished using a chiral manganese porphyrin complex equipped with a remote molecular recognition site. Despite the marginal size difference between the two substituents at the prostereogen
Efficient visible light mediated synthesis of quinolin-2(1H)-ones from quinolineN-oxides
Bhuyan, Samuzal,Chhetri, Karan,Hossain, Jagir,Jana, Saibal,Mandal, Susanta,Roy, Biswajit Gopal
, p. 5049 - 5055 (2021/07/29)
Quinolin-2(1H)-ones are one of the important classes of compounds due to their prevalence in natural products and in pharmacologically useful compounds. Here we present an unconventional and hitherto unknown photocatalytic approach to their synthesis from easily available quinoline-N-oxides. This reagent free highly atom economical photocatalytic method, with low catalyst loading, high yield and no undesirable by-product, provides an efficient greener alternative to all conventional synthesis reported to date. The robustness of the methodology has been successfully demonstrated with easy scaling up to the gram scale.
Preparation method of 2-quinolinone compounds
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Paragraph 0035; 0036; 0037; 0038, (2018/12/05)
The invention provides a preparation method of 2-quinolinone compounds. Quinoline-N-oxide compounds are served as raw materials and react in an organic solvent in the presence of zinc salt served as acatalyst and under the illumination of an xenon lamp, a series of 2-quinolinone compounds are synthesized. The preparation method provided by the invention has the following beneficial effects: as animportant nitrogen-containing heterocyclic compound, the quinolinone compounds are already applied to the fields such as medicine and important reaction intermediates and have a broad prospect in market application. According to the preparation method provided by the invention, quinoline-N-oxides are served as raw materials and react in the organic solvent in the presence of cheap metal salt served as a catalyst and in the condition of illumination, a series of 2-quinolinone compounds are synthesized; the method has the advantages of simple steps, easily available raw materials, mild reactionconditions, accordance to the principles of green chemistry and the like. The preparation method provided by the invention has relatively great use value and social and economic benefits.