939759-05-4 Usage
General Description
8-Chloro-3,4-dihydro-2H-benzo[1,4]oxazine is a chemical compound that belongs to the oxazine family. It is a heterocyclic compound containing a six-membered ring with oxygen and nitrogen atoms. The chlorine atom is attached to the eighth position of the benzo ring. 8-Chloro-3,4-dihydro-2H-benzo[1,4]oxazine has potential pharmaceutical applications and is often used in the synthesis of various organic compounds. It is important for researchers and chemists due to its unique structure and potential biological activities. The compound may be used in the development of new drugs and pharmaceuticals.
Check Digit Verification of cas no
The CAS Registry Mumber 939759-05-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,3,9,7,5 and 9 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 939759-05:
(8*9)+(7*3)+(6*9)+(5*7)+(4*5)+(3*9)+(2*0)+(1*5)=234
234 % 10 = 4
So 939759-05-4 is a valid CAS Registry Number.
939759-05-4Relevant articles and documents
Discovery of a lead series of potent benzodiazepine 5-HT2C receptor agonists with high selectivity in functional and binding assays
Dang, Huong,Feichtinger, Konrad,Frazer, John,Grottick, Andrew J.,Kasem, Michelle,Le, Minh,Lehman, Juerg,Morgan, Michael E.,Ren, Albert,Sage, Carleton R.,Schrader, Thomas O.,Semple, Graeme,Unett, David J.,Whelan, Kevin T.,Wong, Amy,Zhu, Xiuwen
, (2020)
A series of potential new 5-HT2 receptor scaffolds based on a simplification of the clinically studied, 5-HT2CR agonist vabicaserin, were designed. An in vivo feeding assay early in our screening process played an instrumental part in the lead identification process, leading us to focus on a 6,5,7-tricyclic scaffold. A subsequent early SAR investigation provided potent agonists of the 5-HT2C receptor that were highly selective in both functional and binding assays, had good rat PK properties and that significantly reduced acute food intake in the rat.