939986-65-9

Basic information

• Product Name: 6-chloropyrimidine-4-carbonitrile
• Synonyms: 6-chloropyrimidine-4-carbonitrile;T90052
• CAS NO: 939986-65-9
• Molecular Formula: C₅H₂ClN₃
• Molecular Weight: 139.54200
• Mol File: 939986-65-9.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 6-chloropyrimidine-4-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 6-chloropyrimidine-4-carbonitrile(939986-65-9)
• EPA Substance Registry System: 6-chloropyrimidine-4-carbonitrile(939986-65-9)

Safety Data

• Hazardous Substances Data: 939986-65-9(Hazardous Substances Data)

Usage

General Description

6-chloropyrimidine-4-carbonitrile is a chemical compound with the molecular formula C6H2ClN3. It is a derivative of pyrimidine and contains a chloro and cyano group on the 4th and 6th carbon atoms, respectively. This chemical is commonly used in the pharmaceutical industry as an intermediate for the synthesis of various biologically active compounds. It is also used as a building block in the production of agrochemicals and other fine chemicals. 6-chloropyrimidine-4-carbonitrile is known for its versatile reactivity and is utilized in the development of different chemical processes for the production of valuable products in pharmaceutical and agricultural applications.

Upstream product

• 121-69-7 N,N-dimethyl-aniline 
• 1370442-07-1 6-hydroxy-pyrimidine-4-carbaldehyde oxime 
• 98024-63-6 6-hydroxy-4-pyrimidinecarboxamide 
• 223788-14-5 ethyl 6-oxo-3,6-dihydropyrimidine-4-carboxylate 

Downstream Products

• 2226735-55-1 (S)-6-(4-(5-(3,5-difluorophenyl)-4,5-dihydro-1H-pyrazole-1-carbonyl)piperidin-1-yl)pyrimindine-4-carbonitrile 

Relevant articles and documents

(3-phenylisoxazolidin-2-yl)(piperidin-4-yl)methanone derivatives and pharmaceutical composition for use in preventing or treating kinase-related disease

The present invention relates to a (3-phenylisoxazolidin-2-yl)(piperidin-4-yl)methanone derivative represented by the following chemical formula 1, and a pharmaceutical composition for treating kinase-related diseases including the same as an active ingredient. The (3-phenylisoxazolidin-2-yl)(piperidin-4-yl)methanone derivative according to one aspect shows an excellent activity of inhibiting at least one kinase selected from the group consisting of ABL1, ABL2, BRAF, CDK11, CDK8, CDKL2, CIT, CSF1R, DDR1, DDR2, FLT3, KIT, LOK, LTK, MUSK, PAK3, PDGFRA, PDGFRB, RAF1 and RIPK1, and thus can be used for treating kinase-related diseases.

SUBSTITUTED ALKYLAMINE DERIVATIVES AND METHODS OF USE

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