943767-91-7Relevant articles and documents
LSD1 INHIBITORS
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Paragraph 0212, (2017/05/20)
The present invention relates to compounds that inhibit LSD1 activity. In particular, the present invention relates to compounds, pharmaceutical compositions and methods of use, such as methods of treating cancer using the compounds and pharmaceutical com
Synthesis of N1 -alkyl-1,4-diazepin-5-ones via Schmidt ring expansion chemistry
Frick, Morin,McAtee, Danielle,McAtee, Jesse,Wysoczynski, Christina,Ray, Partha S.
experimental part, p. 17 - 19 (2011/10/02)
Reaction of 4-piperidone with alkyl bromides gave the corresponding N-alkyl-4-piperidones, and treatment of these with hydrazoic acid resulted in the Schmidt reaction to give the corresponding N1-alkyl-1,4-diazepin- 5-ones in good overall yield