944125-07-9Relevant articles and documents
Intramolecular addition of carbon radicals to aldehydes: synthesis of enantiopure tetrahydrofuran-3-ols
Tiecco, Marcello,Testaferri, Lorenzo,Marini, Francesca,Sternativo, Silvia,Santi, Claudio,Bagnoli, Luana,Temperini, Andrea
, p. 5482 - 5489 (2008/01/07)
A simple and efficient substrate-controlled asymmetric synthesis of enantiopure tetrahydrofuran-3-ols by a 5-exo-trig radical cyclization is described. This cyclization occurs when a δ-carbon radical adds intramolecularly to the carbonyl group of an aldeh