94467-73-9

Basic information

• Product Name: MORPHOLIN-4-YL-PIPERIDIN-4-YL-METHANONE HYDROCHLORIDE
• Synonyms: 4-(4-PIPERIDYLCARBONYL)MORPHOLINE HYDROCHLORIDE;4-(PIPERIDIN-4-YLCARBONYL)MORPHOLINE HYDROCHLORIDE;MORPHOLIN-4-YL-PIPERIDIN-4-YL-METHANONE HYDROCHLORIDE;MORPHOLINO(4-PIPERIDINYL)METHANONE HYDROCHLORIDE;4-(Piperid-4-ylcarbonyl)morpholine hydrochloride;Morpholin-4-yl-piperidin-4-yl-methanoneHCl95%;Morpholin-4-yl-piperidin-4-yl-methanonehydrochloride95%;4-(Piperid-4-ylcarbonyl)morpholine hydrochloride 90%
• CAS NO: 94467-73-9
• Molecular Formula: C10H19ClN2O2
• Molecular Weight: 234.72
• EINECS: 604-604-1
• Mol File: 94467-73-9.mol
• Article Data: 2

Chemical Properties

• Melting Point: 279-286
• Boiling Point: 369.8 °C at 760 mmHg
• Flash Point: 177.4 °C
• Appearance: /
• Vapor Pressure: 1.16E-05mmHg at 25°C
• CAS DataBase Reference: MORPHOLIN-4-YL-PIPERIDIN-4-YL-METHANONE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: MORPHOLIN-4-YL-PIPERIDIN-4-YL-METHANONE HYDROCHLORIDE(94467-73-9)
• EPA Substance Registry System: MORPHOLIN-4-YL-PIPERIDIN-4-YL-METHANONE HYDROCHLORIDE(94467-73-9)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 94467-73-9(Hazardous Substances Data)

Usage

General Description

Morpholin-4-yl-piperidin-4-yl-methanone hydrochloride is a chemical compound that is used in the synthesis of pharmaceutical drugs and other organic compounds. It is a crystalline solid with a molecular formula of C12H21ClN2O and a molecular weight of 240.77 g/mol. This chemical is primarily used as an intermediate in the production of various medications, such as antihistamines and antipsychotic drugs. It has applications in the pharmaceutical industry as a building block for the synthesis of various bioactive compounds. Additionally, it may also be used in research and development for the creation of new drugs and chemical entities.

InChI:InChI=1/C10H18N2O2.ClH/c13-10(9-1-3-11-4-2-9)12-5-7-14-8-6-12;/h9,11H,1-8H2;1H

Upstream product

• 52482-36-7 morpholin-4-yl(pyridin-4-yl)methanone 
• 110-91-8 morpholine 
• 5984-56-5 piperidine-4-carboxylic acid hydrochloride 

Relevant articles and documents

Novel methanone derivatives, preparation method thereof, and pharmaceutical composition for use in preventing or treating blindness related diseases containing the same as an active ingredient

The present invention relates to novel methanone derivatives, a preparation method thereof, and a pharmaceutical composition comprising the same as an active ingredient for preventing or treating retinal diseases. Since the novel methanone derivatives according to the present invention, optical isomers thereof or pharmaceutically acceptable salts thereof have an excellent effect of inhibiting receptor-interacting serine/threonine-protein kinase 1 (RIPK1), the composition comprising the same as an active ingredient can be advantageously used as a pharmaceutical composition for preventing or treating retinal diseases such as retinitis pigmentosa (RP), Leberandprime;s congenital amaurosis (LCA), Stargardts disease, Usher syndrome, choroideremia, rod-cone or cone-rod dystrophy, ciliopathies, a mitochondrial disorder, progressive retinal atrophy, a degenerative retinal disease, age-related macular degeneration (AMD), wet AMD, dry AMD, geographic atrophy, hereditary or acquired maculopathy, a retinal photoreceptor disease, a retinal pigment epithelial disease, diabetic retinopathy, cystic macular edema, uveitis, retinal detachment, traumatic retinal damage, iatrogenic retinal damage, a macular hole, macular capillary ectasia, a ganglion cell disease, an optic nerve disease, glaucoma, optic neuropathy, ischemic retinal disease , retinopathy of prematurity (ROP), retinal vascular occlusion, hereditary macroaneurysm, a retinal vascular disease , an ophthalmovascular disease, degeneration of retinal neuronal cells caused by glaucoma, or ischemic optic neuropathy.COPYRIGHT KIPO 2015