945452-29-9

Basic information

• Product Name: 4-[(2,4-diamino-5-ethyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)sulfanyl]benzoic acid
• Synonyms: 4-[(2,4-diamino-5-ethyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)sulfanyl]benzoic acid
• CAS NO: 945452-29-9
• Molecular Weight: 329.382
• Mol File: 945452-29-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-[(2,4-diamino-5-ethyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)sulfanyl]benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[(2,4-diamino-5-ethyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)sulfanyl]benzoic acid(945452-29-9)
• EPA Substance Registry System: 4-[(2,4-diamino-5-ethyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)sulfanyl]benzoic acid(945452-29-9)

Safety Data

• Hazardous Substances Data: 945452-29-9(Hazardous Substances Data)

Upstream product

• 1074-36-8 4-mercaptobenzoic acid 
• 170170-14-6 2,4-Diamino-5-ethylpyrrolo<2,3-d>pyrimidine 

Downstream Products

• 945452-30-2 diethyl N-{4-[(5-ethyl-2-amino-3,4-dihydro-4-oxo-7H-pyrrolo[2,3-d]pyrimidin-6-yl)thio]benzoyl}-L-glutamate 

Relevant articles and documents

Design and synthesis of classical and nonclassical 6-arylthio-2,4-diamino- 5-ethylpyrrolo[2,3-d]pyrimidines as antifolates

The classical antifolate N-{4-[(2,4-diamino-5-ethyl-7H-pyrrolo[2,3-d] pyrimidin-6-yl)sulfanyl]benzoyl}-L-glutamic acid (2) and 15 nonclassical analogues (3-17) were synthesized as potential dihydrofolate reductase (DHFR) inhibitors and as antitumor agents