945863-21-8

Basic information

• Product Name: 2-(N-Methylaminocarbonyl)-5-pyridineboronic acid pincol ester
• Synonyms: 2-(N-Methylaminocarbonyl)-5-pyridineboronic acid pincol ester;2-(N-Methylaminocarbonyl)pyridine-5-boronic acidpincol ester;2-(N-Methylaminocarbonyl)pyridine-5-boronic acid pinacol ester;7 2-(N-Methylaminecarbonyl)-5-pyridineboronic acid pincol;6-(Methylcarbamoyl)pyridine-3-boronic acid, pinacol ester;N-Methyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)picolinaMide;2-(Methylcarbamoyl)pyridine-5-boronic acid, pinacol ester, 6-(Methylaminocarbonyl)pyridine-3-boronic acid, pinacol ester, N-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-2-carboxamide;2-N-Methylaminecarbonyl-5-pyridineboronic acid pinacol ester
• CAS NO: 945863-21-8
• Molecular Formula: C₁₃H₁₉BN₂O₃
• Molecular Weight: 262.11
• Product Categories: Organoborons;Pyridine
• Mol File: 945863-21-8.mol
• Article Data: 5

Chemical Properties

• Melting Point: 113-115℃
• Boiling Point: 427.7±30.0 °C(Predicted)
• Appearance: /
• Density: 1.11±0.1 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 14.25±0.46(Predicted)
• Water Solubility: Slightly soluble in water.
• CAS DataBase Reference: 2-(N-Methylaminocarbonyl)-5-pyridineboronic acid pincol ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(N-Methylaminocarbonyl)-5-pyridineboronic acid pincol ester(945863-21-8)
• EPA Substance Registry System: 2-(N-Methylaminocarbonyl)-5-pyridineboronic acid pincol ester(945863-21-8)

Safety Data

• Hazardous Substances Data: 945863-21-8(Hazardous Substances Data)

Usage

Description

2-(N-Methylaminocarbonyl)-5-pyridineboronic acid pincol ester is an organic compound that serves as a key intermediate in the synthesis of various pharmaceuticals. It is characterized by its unique chemical structure, which includes a pyridine ring, a boronic acid group, and a pincol ester moiety. 2-(N-Methylaminocarbonyl)-5-pyridineboronic acid pincol ester plays a crucial role in the development of new drugs and therapeutic agents.

Uses

Used in Pharmaceutical Industry:
2-(N-Methylaminocarbonyl)-5-pyridineboronic acid pincol ester is used as a pharmaceutical intermediate for the synthesis of various drugs and therapeutic agents. Its unique chemical structure allows it to be a versatile building block in the development of new medications, particularly those targeting specific biological pathways or receptors.
As a pharmaceutical intermediate, 2-(N-Methylaminocarbonyl)-5-pyridineboronic acid pincol ester is utilized in the synthesis of compounds with potential applications in treating a wide range of diseases and conditions. Its presence in the final drug product may contribute to the overall efficacy, safety, and pharmacokinetic properties of the medication.

Upstream product

• 845305-87-5 5-bromo-2-(N-methylaminocarbonyl)pyridine 
• 73183-34-3 bis(pinacol)diborane 

Downstream Products

• 1029713-58-3 5-{2-fluoro-4-[3-(1-quinolin-6-ylcyclopropyl)imidazo[1,2-a]pyrimidin-6-yl]phenyl}-N-methylpyridine-2-carboxamide 
• 1029713-67-4 N-methyl-5-{4-[7-(1-quinolin-6-ylcyclopropyl)imidazo[1,2-b][1,2,4]triazin-2-yl]phenyl}pyridine-2-carboxamide 
• 1093751-40-6 5-3-fluoro-4-[(5S)-2-(cis-4-hydroxycyclohexyl)-1-oxo-2,7-diazaspiro[4.5]dec-7-yl]phenyl-N-methylpyridine-2-carboxamide 
• 1200498-32-3 C₂₃H₂₆F₂N₄O₃S 
• 1332448-72-2 5-(2-(2,8-dimethyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)phenyl)-N-methylpicolinamide 
• 1332448-80-2 5-(3-(2,8-dimethyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)phenyl)-N-methylpicolinamide 
• 1610611-12-5 N-(4-cyanophenyl)-N-methyl-3-(6-(methylcarbamoyl)pyridin-3-yl)pyrazolo[1,5-a]pyridine-5-carboxamide 
• 1610612-38-8 tert-butyl 2-(4-cyanophenyl)-1-methyl-2-(3-(6-(methylcarbamoyl)pyridin-3-yl)pyrazolo[1,5-a]pyridine-5-carbonyl)hydrazinecarboxylate 
• 1610611-24-9 N-(4-chlorophenyl)-N-methyl-3-(6-(methylcarbamoyl)pyridin-3-yl)pyrazolo[1,5-a]pyridine-5-carboxamide 
• 2009273-71-4 5-[6-amino-4-ethyl-5-(4-hydroxyphenyl)-3-pyridyl]-N-methylpyridine-2-carboxamide 

Relevant articles and documents

A 2-amino-thiazole compounds (by machine translation)

The present invention relates to the technical field of pharmaceutical chemistry, particularly relates to a 2-amino thiazole compound or its pharmaceutically acceptable salts, its preparation method, and pharmaceutical compositions containing such compounds and its application in the preparation of antineoplastic. (by machine translation)

NOVEL 3,5-DISUBSTITUED-3H-IMIDAZO[4,5-B]PYRIDINE AND 3,5- DISUBSTITUED -3H-[1,2,3]TRIAZOLO[4,5-B] PYRIDINE COMPOUNDS AS MODULATORS OF C-MET PROTEIN KINASES

The present invention provides compounds useful as C-met protein kinase modulators, methods of preparing them, pharmaceutical compositions containing them and methods of treatment, prevention and/or amelioration of C-met kinase mediated diseases or disorders with them.

PI3K/M TOR INHIBITORS

The invention relates to PI3K/mTOR inhibiting compounds consisting of the formula (I): wherein the variables are as defined herein. The invention also relates to pharmaceutical compositions, kits and articles of manufacture comprising such compounds; meth