946000-01-7

Basic information

• Product Name: trans-methyl 4-(3-{[[4-(tert-butoxycarbonyl-methyl-amino)-cyclohexyl]-(3-chloro-4,7-difluoro-benzo[b]thiophene-2-carbonyl)-amino]-methyl}-4-methoxy-phenyl)-pyridine-2-carboxylate
• Synonyms: trans-methyl 4-(3-{[[4-(tert-butoxycarbonyl-methyl-amino)-cyclohexyl]-(3-chloro-4,7-difluoro-benzo[b]thiophene-2-carbonyl)-amino]-methyl}-4-methoxy-phenyl)-pyridine-2-carboxylate
• CAS NO: 946000-01-7
• Molecular Weight: 714.23
• Mol File: 946000-01-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: trans-methyl 4-(3-{[[4-(tert-butoxycarbonyl-methyl-amino)-cyclohexyl]-(3-chloro-4,7-difluoro-benzo[b]thiophene-2-carbonyl)-amino]-methyl}-4-methoxy-phenyl)-pyridine-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: trans-methyl 4-(3-{[[4-(tert-butoxycarbonyl-methyl-amino)-cyclohexyl]-(3-chloro-4,7-difluoro-benzo[b]thiophene-2-carbonyl)-amino]-methyl}-4-methoxy-phenyl)-pyridine-2-carboxylate(946000-01-7)
• EPA Substance Registry System: trans-methyl 4-(3-{[[4-(tert-butoxycarbonyl-methyl-amino)-cyclohexyl]-(3-chloro-4,7-difluoro-benzo[b]thiophene-2-carbonyl)-amino]-methyl}-4-methoxy-phenyl)-pyridine-2-carboxylate(946000-01-7)

Safety Data

• Hazardous Substances Data: 946000-01-7(Hazardous Substances Data)

Upstream product

• 112898-33-6 3-(2,5-difluorophenyl)acrylic acid 
• 19524-06-2 4-bromopyridine hydrochloride 
• 2615-25-0 trans-1,4-cyclohexyldiamine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 945996-91-8 trans-3-{[4-(Boc-methyl-amino)-cyclohexylamino]-methyl}-4-methoxy-benzeneboronic acid 
• 566172-78-9 n-butyl trans-(4-aminocyclohexyl)-carbamate 
• 566172-79-0 trans-N-methyl-N-tert-butoxycarbonyl-1,4-diaminocyclohexane 
• 15803-59-5 (1r,4r)-N¹-methylcyclohexane-1,4-diamine 
• 566172-81-4 3-chloro-4,7-difluoro-benzo[b]thiophene-2-carbonyl chloride 
• 945996-98-5 trans-3-{[[4-(Boc-methyl-amino)-cyclohexyl]-(3-chloro-4,7-difluoro-benzo[b]thiophene-2-carbonyl)-amino]-methyl}-4-methoxy-benzeneboronic acid 
• 29681-42-3 methyl 4-bromopyridine-2-carboxylate 

Downstream Products

• 946000-09-5 trans-tert-butyl (4-{(3-chloro-4,7-difluoro-benzo[b]thiophene-2-carbonyl)-[2-methoxy-5-(2-methylcarbamoyl-pyridin-4-yl)-benzyl]-amino}-cyclohexyl)-methyl-carbamate 
• 946000-02-8 trans-methyl 4-(3-{[(3-chloro-4,7-difluoro-benzo[b]thiophene-2-carbonyl)-(4-methylamino-cyclohexyl)-amino]-methyl}-4-methoxy-phenyl)-pyridine-2-carboxylate 
• 946000-03-9 trans-tert-butyl {4-[[5-(2-carbamoyl-pyridin-4-yl)-2-methoxy-benzyl]-(3-chloro-4,7-difluoro-benzo[b]thiophene-2-carbonyl)-amino]-cyclohexyl}-methyl-carbamate 
• 1025061-31-7 trans-{4-[[5-(2-acetyl-pyridin-4-yl)-2-methoxy-benzyl]-(3-chloro-4,7-difluoro-benzo[b]thiophene-2-carbonyl)-amino]-cyclohexyl}-methyl-carbamic acid tert-butyl ester 

Relevant articles and documents

SMALL ORGANIC MOLECULE REGULATORS OF CELL PROLIFERATION

The present invention makes available methods and reagents for modulating proliferation or differentiation in a cell or tissue comprising contacting the cell with a compound. In certain embodiments, the methods and reagents may be employed to correct or inhibit an aberrant or unwanted growth state, e.g., by antagonizing a normal patched pathway or agonizing smoothened orhedgehog activity.