947590-62-7Relevant articles and documents
Studies of benzothiophene template as potent factor IXa (FIXa) inhibitors in thrombosis
Wang, Shouming,Beck, Richard,Blench, Toby,Burd, Andrew,Buxton, Stuart,Malic, Maja,Ayele, Tenagne,Shaikh, Shaheda,Chahwala, Suresh,Criandera, Chaman,Holland, Richard,Merette, Sandrine,Zhao, Lihua,Blackney, Michael,Watts, Alexandra
experimental part, p. 1465 - 1472 (2010/07/05)
FIXa is a serine protease enzyme involved in the intrinsic pathway of the coagulation cascade. The upstream intervention of the coagulation cascade in selectively inhibiting FIXa would leave hemostasia intact via the extrinsic pathway, leading to an optim