94790-24-6

Basic information

• Product Name: oc-O-Methyl-L-TyrosineMethylEster
• Synonyms: oc-O-Methyl-L-TyrosineMethylEster;METHYL (2R)-2-[(TERT-BUTOXY)CARBONYLAMINO]-3-(4-METHOXYPHENYL)PROPANOATE;Methyl N-Boc-O-methyl-L-tyrosinate;(S)-2-[(tert-Butoxycarbonyl)amino]-3-(4-methoxyphenyl)propionic acid methyl ester;N-tert-Butoxycarbonyl-O-methyl-L-tyrosine methyl ester;O-methyl-N-tert-butoxycarbonyl-L-tyrosine methyl ester;Boc-4-methoxy-L-phenylalanine methyl ester;Boc-L-Tyr(Me)-OMe
• CAS NO: 94790-24-6
• Molecular Formula: C₁₆H₂₃NO₅
• Molecular Weight: 309.36
• Mol File: 94790-24-6.mol
• Article Data: 47

Chemical Properties

• Appearance: /
• CAS DataBase Reference: oc-O-Methyl-L-TyrosineMethylEster(CAS DataBase Reference)
• NIST Chemistry Reference: oc-O-Methyl-L-TyrosineMethylEster(94790-24-6)
• EPA Substance Registry System: oc-O-Methyl-L-TyrosineMethylEster(94790-24-6)

Safety Data

• Hazardous Substances Data: 94790-24-6(Hazardous Substances Data)

Usage

Description

oc-O-Methyl-L-TyrosineMethylEster is a chemical compound derived from the amino acid tyrosine, specifically as an ester derivative of 3-O-methyl-L-tyrosine. It is primarily utilized in the fields of organic chemistry and biochemistry for research purposes. oc-O-Methyl-L-TyrosineMethylEster has demonstrated potential pharmacological properties, making it a promising candidate for drug development. Furthermore, it has been investigated for its possible therapeutic role in the treatment of specific neurological and psychiatric disorders. However, additional research is necessary to fully comprehend its biological activities and potential applications in medicine.

Uses

Used in Organic Chemistry Research:
oc-O-Methyl-L-TyrosineMethylEster is used as a research compound in organic chemistry for studying its chemical properties and potential reactions with other molecules.
Used in Biochemical Research:
In biochemistry, oc-O-Methyl-L-TyrosineMethylEster serves as a research tool to explore its interactions with biological systems and understand its role in various biochemical processes.
Used in Drug Development:
oc-O-Methyl-L-TyrosineMethylEster is used as a potential candidate in drug development due to its demonstrated pharmacological properties, which may lead to the creation of new therapeutic agents.
Used in Pharmaceutical Industry:
Within the pharmaceutical industry, oc-O-Methyl-L-TyrosineMethylEster is utilized for the development and testing of new drugs, particularly those targeting neurological and psychiatric disorders.
Used in Treatment of Neurological and Psychiatric Disorders:
oc-O-Methyl-L-TyrosineMethylEster is studied for its potential role in the treatment of certain neurological and psychiatric disorders, with the aim of providing new therapeutic options for patients.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 17355-19-0 methyl (R)-2-amino-3-(4-methoxyphenyl)propanoate 
• 76757-90-9 N-(tert-butoxycarbonyl)-D-tyrosine methyl ester 
• 77-78-1 dimethyl sulfate 
• 74-88-4 methyl iodide 
• 70642-86-3 N-(tert-butoxycarbonyl)-D-tyrosine 
• 556-02-5 tyrosine 
• 3728-20-9 D-tyrosine methylester hydrochloride 
• 241153-85-5 methyl 3-(3-chloro-4-methoxyphenyl)acrylate 
• 1415012-36-0 methyl 2,3-dihydroxy3-(3-chloro-4-methoxyphenyl)propanoate 
• 830-09-1 3-(4'-methoxyphenyl)propenoic acid 
• 832-01-9 methyl p-methoxycinnamate 
• 122517-81-1 (2R,3S)-methyl 2,3-dihydroxy-3-(4-methoxyphenyl)propanoate 
• 1415012-34-8 methyl 2-azido-3-(4-methoxyphenyl)propanoate 

Downstream Products

• 68856-96-2 N-(tert-butoxycarbonyl)-O-methyl-D-tyrosine 
• 120349-75-9 (2R)-2-(tert-butoxycarbonyl)amino-3-(4-methoxyphenyl)propan-1-ol 
• 17355-19-0 methyl (R)-2-amino-3-(4-methoxyphenyl)propanoate 
• 162600-54-6 cryptophycin-24 
• 733769-88-5 (R)-2-Acryloylamino-3-(4-methoxy-phenyl)-propionic acid methyl ester 
• 733769-89-6 3-[(R)-2-Acryloylamino-3-(4-methoxy-phenyl)-propionylamino]-propionic acid 
• 1027261-48-8 3-[(R)-2-Acryloylamino-3-(4-methoxy-phenyl)-propionylamino]-propionic acid ethyl ester 
• 1026015-46-2 (S)-2-{3-[(R)-2-Acryloylamino-3-(4-methoxy-phenyl)-propionylamino]-propionyloxy}-4-methyl-pentanoic acid 
• 733769-90-9 (S)-2-{3-[(R)-2-Acryloylamino-3-(4-methoxy-phenyl)-propionylamino]-propionyloxy}-4-methyl-pentanoic acid tert-butyl ester 
• 733769-83-0 (S)-2-{3-[(R)-2-Acryloylamino-3-(4-methoxy-phenyl)-propionylamino]-propionyloxy}-4-methyl-pentanoic acid (S)-1-[(S)-1-((2R,3R)-3-phenyl-oxiranyl)-ethyl]-but-3-enyl ester 
• 27958-06-1 (2R,3S,4S)-3,4-dihydroxy-2-(4-methoxybenzyl)pyrrolidine 
• 139183-60-1 [(R)-1-Formyl-2-(4-methoxy-phenyl)-ethyl]-carbamic acid tert-butyl ester 
• 228396-55-2 (1R,4S,5R)-5-[1-(tert-butoxycarbonyl)amino-2-(4-methoxyphenyl)ethyl]-2,2-dimethyl-1,3-dioxolan-4-ylmethanol 
• 478623-17-5 ethyl (2E,4R)-4-(tert-butoxycarbonyl)amino-5-(4-methoxyphenyl)pent-2-enoate 

Relevant articles and documents

Preparation method of chiral alpha-methyl arylethylamine

The invention provides a preparation method of chiral alpha-methyl arylethylamine, and relates to the technical field of organic synthesis medicines. Boc-amino acid methyl ester is used as an initial raw material, Boc-amino alcohol is obtained through reduction, Boc-amino alcohol reacts with thionyl chloride and is oxidized through sodium periodate to obtain a sulfonamide compound, and then the sulfonamide compound is reduced through sodium borohydride promoted by lewis acid and a protecting group is removed under the acidic condition to obtain a target compound. According to the method, raw materials are cheap and easy to obtain, a single optical isomer product is obtained by using chiral raw materials, the problem of column chromatography resolution is solved, generation of a large amount of solid wastes and isomers is avoided, atom economy is improved, the product purity is high, the yield is high, and the production cost is effectively reduced. In addition, the mild reduction system is used for replacing the original high-pressure hydrogenation reaction, the process operation is relatively simple, and the method is more suitable for large-scale industrial production.

BORYLATED AMINO ACID COMPOSITIONS FOR USE IN BORON NEUTRON CAPTURE THERAPY AND METHODS THEREOF

Borylated Amino Acid ("BAA") compositions and methods of making BAAs are disclosed herein. Consequently, the BAAs can be administered to patients as a Neutron Capture Agent and provide a method of treating cancer, immunological disorders and other disease by utilizing a Neutron Capture Therapy modality.

Rapid Syntheses of (?)-FR901483 and (+)-TAN1251C Enabled by Complexity-Generating Photocatalytic Olefin Hydroaminoalkylation

We report a common strategy to facilitate the syntheses of the polycyclic alkaloids (?)-FR901483 (1) and (+)-TAN1251C (2). A divergent synthetic strategy provides access to both natural products through a pivotal spirolactam intermediate (3), which can be accessed on a gram-scale. A photocatalytic olefin hydroaminoalkylation brings together three readily available building blocks and forges the majority of the carbon framework present in 1 and 2 in a single operation, leading to concise total syntheses. The complexity-generating photocatalytic process also provides direct access to novel non-racemic spirolactam scaffolds that are likely to be of interest to early-stage drug discovery programs.