948043-99-0Relevant articles and documents
Synthetic method of directly coupling aryl halide by aromatic hydrocarbon Grignard reagent in the presence of recycled modified palladium-charcoal
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Paragraph 0012; 0013; 0014, (2016/10/08)
The invention provides a synthetic method of directly coupling aryl halide by an aromatic hydrocarbon Grignard reagent. The synthetic method includes performing reflux and water separation of a catalyst Pd/C and an azeotropic organic solvent of non-halogenated hydrocarbon and water, adding an organic phosphine ligand, performing a complexation reaction to obtain a catalyst organic phosphine ligand complexing Pd/C, using aryl halide as an initial material, performing a Grignard reaction at 10-90 DEG C to obtain a Grignard reagent, adding the catalyst, performing a coupled reaction of aryl halide and the Grignard reagent to obtain a coupling aromatic hydrocarbon. The synthetic method uses one-step method, has low synthesis cost, is green and environmental friendly, and is a high-efficiency and clean synthetic technology of coupling aryl halide.
Ethyl- and vinylbenzenes as antithromobiotic agents
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, (2008/06/13)
A method of treating vascular thrombosis in warmblooded animals, employing an ethyl- or vinylbenzene as the active antithrombotic agent.