949160-14-9

Basic information

• Product Name: 2-Bromo-6-tert-butylOXY-pyridine
• Synonyms: 2-Bromo-6-tert-butylOXY-pyridine;6-(TERT-BUTOXY)-2-BROMOPYRIDINE;2-BROMO-6-(TERT-BUTOXY)PYRIDINE;2-tert-Butoxy-6-bromopyridine
• CAS NO: 949160-14-9
• Molecular Formula: C₉H₁₂BrNO
• Molecular Weight: 230.11
• Mol File: 949160-14-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 247.706 °C at 760 mmHg
• Flash Point: 103.609 °C
• Appearance: /
• Density: 1.335 g/cm³
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -0.24±0.12(Predicted)
• CAS DataBase Reference: 2-Bromo-6-tert-butylOXY-pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-6-tert-butylOXY-pyridine(949160-14-9)
• EPA Substance Registry System: 2-Bromo-6-tert-butylOXY-pyridine(949160-14-9)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-37/39
• Hazardous Substances Data: 949160-14-9(Hazardous Substances Data)

Usage

Chemical Properties

Clear colorless liquid

InChI:InChI:1S/C9H12BrN/c1-9(2,3)7-5-4-6-8(10)11-7/h4-6H,1-3H3

Upstream product

• 626-05-1 2,6-Dibromopyridine 
• 865-47-4 potassium tert-butylate 

Relevant articles and documents

Tandem radical reactions of isonitriles with 2-pyridonyl and other aryl radicals: Scope and limitations, and a first generation synthesis of (±)-camptothecin

Photolysis of N-propargyl-6-halo-2-pyridones and related aromatic halides in the presence of aryl isonitriles provides tetra- and penta-cyclic products in a single step by a sequence of radical addition to the isonitrile followed by two cyclizations. The scope and limitations of the process are described along with a first generation synthesis of racemic camptothecin.