94929-80-3Relevant articles and documents
Oxazolone-based photoswitches: Synthesis and properties
Blanco-Lomas, Marina,Funes-Ardoiz, Ignacio,Campos, Pedro J.,Sampedro, Diego
, p. 6611 - 6618 (2013)
The synthesis, photophysics and photochemistry of a family of molecular switches inspired by the green fluorescent protein (GFP) chromophore is presented. These compounds can be synthesized in one step and good yields, their photophysical properties may b
Benzylidene-oxazolones as photoswitches: Photochemistry and theoretical calculations
Funes-Ardoiz, Ignacio,Blanco-Lomas, Marina,Campos, Pedro J.,Sampedro, Diego
supporting information, p. 9766 - 9771 (2013/10/22)
The photophysics and photochemistry of a family of compounds proposed as efficient molecular photoswitches is presented. The effect of different light sources, substituents and solvents in the photostationary state has been explored. A detailed mechanisti
Pseudo-peptides derived from isomannide: Inhibitors of serine proteases
Barros, Thalita G.,Pinheiro, Sergio,Williamson,Tanuri, Amilcar,Gomes Jr.,Pereira, Helena S.,Brindeiro,Neto, Jose B. A.,Antunes,Muri, Estela M. F.
scheme or table, p. 701 - 709 (2010/08/05)
In this paper, we describe the synthesis of a novel class of pseudo-peptides derived from isomannide and several oxazolones as potential inhibitors of serine proteases as well as preliminary pharmacological assays for hepatitis C. Hepatitis C, dengue and West Nile fever are among the most important flaviviruses that share one important serine protease enzyme. Serine proteases belong to the most studied class of proteolytic enzymes and are a primary target in the drug development field. Several pseudo-peptides were obtained in good yields from the reaction of isomannide and oxazolones, and their anti-HCV potential using the HCV replicon-based assay was shown.