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952238-93-6

952238-93-6

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952238-93-6 Usage

General Description

PF 477736 (HCl) is a potent and selective inhibitor of the checkpoint kinase 1 (Chk1), which plays a crucial role in the DNA damage response and cell cycle regulation. It is commonly used in research to study the function of Chk1 and its potential as a therapeutic target in cancer treatment. PF 477736 has been shown to inhibit the phosphorylation of Chk1 and disrupt the cell cycle, leading to a halt in cell proliferation and ultimately inducing apoptosis in cancer cells. Due to its promising anti-cancer properties, PF 477736 has been the focus of numerous studies and clinical trials for its potential as a novel cancer treatment.

Check Digit Verification of cas no

The CAS Registry Mumber 952238-93-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,5,2,2,3 and 8 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 952238-93:
(8*9)+(7*5)+(6*2)+(5*2)+(4*3)+(3*8)+(2*9)+(1*3)=186
186 % 10 = 6
So 952238-93-6 is a valid CAS Registry Number.

952238-93-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name (2R)-2-Amino-2-cyclohexyl-N-[2-(1-methyl-1H-pyrazol-4-yl)-6-oxo-5 ,6-dihydro-1H-[1,2]diazepino[4,5,6-cd]indol-8-yl]acetamide dihydr ochloride

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:952238-93-6 SDS

952238-93-6Upstream product

952238-93-6Downstream Products

952238-93-6Relevant articles and documents

DIAZEPINOINDOLE DERIVATIVES AS KINASE INHIBITORS

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Page 257, (2008/06/13)

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