952301-65-4

Basic information

• Product Name: C₂₃H₃₃N₂OPS
• Synonyms: C₂₃H₃₃N₂OPS
• CAS NO: 952301-65-4
• Molecular Weight: 416.568
• Mol File: 952301-65-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₂₃H₃₃N₂OPS(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₃H₃₃N₂OPS(952301-65-4)
• EPA Substance Registry System: C₂₃H₃₃N₂OPS(952301-65-4)

Safety Data

• Hazardous Substances Data: 952301-65-4(Hazardous Substances Data)

Upstream product

• 114369-15-2 2-(4-bromophenyl)ethyl methanesulfonate 
• 15221-61-1 2-(4-bromophenyl)-N,N-dimethylethan-1-amine 
• 4654-39-1 4-bromophenethanol 
• 952301-53-0 bis{4-[(N,N-dimethylamino)ethyl]phenyl}phosphine tris(borane) 

Relevant articles and documents

Water-soluble phosphinothiol reagents

Water soluble reagents and methods for the formation of an amide bond between a phosphinothioester and an azide in an aqueous medium. The phosphinothioester is generated using a water-soluble phosphinothiol reagent. This reaction allows formation of an amide bond between a wide variety of chemical species including amino acids, peptides or protein fragments in an aqueous solution. Of particular interest, this reaction allows for the formation of an amide bond in a physiological setting. In a specific embodiment, this invention provides reagents and methods for peptide ligation in an aqueous medium. The reaction eliminates the need for a cysteine residue and is traceless leaving no residual atoms in the ligated peptide product.