95466-12-9Relevant articles and documents
Photocatalytic Annulation-Alkynyl Migration Strategy for Multiple Functionalization of Dual Unactivated Alkenes
Zhao, Qi,Hao, Wen-Juan,Shi, Hao-Nan,Xu, Ting,Tu, Shu-Jiang,Jiang, Bo
, p. 9784 - 9789 (2019)
A novel photoredox catalysis for multiple functionalization of two different types of unactivated alkenes in a single operation was reported through a conceptually new mode of annulation-alkynyl migration. A wide array of cyclopentane carboxylates were sy
Alkynylation of aldehydes mediated by zinc and allyl bromide: a practical synthesis of propargylic alcohols
Zhou, Ji-Cai,Zhao, Lei,Li, Yuan,Fu, Ding-Qiang,Li, Zi-Cheng,Huang, Wen-Cai
, p. 4283 - 4294 (2017/06/20)
Abstract: A practical synthesis of propargylic alcohols was developed by alkynylation of aldehydes mediated by zinc and allyl bromide. Aromatic, aliphatic and vinyl aldehydes react with phenylacetylene or 1-hexyne to obtain various propargylic alcohols at room temperature in up to 98% yield. This method is characterized with inexpensive materials, wide substrate scope, and mild reaction conditions, and is also easy to scale up. In addition, this protocol is applicable to the alkynylation of α-ketone esters and epoxides to generate α-tertiary-hydroxy esters and α-alkynyl alcohols, respectively. Graphical Abstract: [Figure not available: see fulltext.].
P(PhCH2NCH2CH2)3N: An efficient Lewis base catalyst for the synthesis of propargylic alcohols and Morita-Baylis-Hillman adducts via aldehyde alkynylation
Wadhwa, Kuldeep,Chintareddy, Venkat Reddy,Verkade, John G.
supporting information; experimental part, p. 6681 - 6690 (2009/12/30)
(Chemical Equation Presented) Proazaphosphatrane P(PhCH2NCH 2CH2)3N (1a) is an efficient catalyst for the addition of aryl trimethylsilyl alkynes to a variety of aromatic, aliphatic, and heterocyclic aldehydes i