955-75-9

Basic information

• Product Name: 2-(4-fluorophenyl)-7-methylimidazo[1,2-a]pyrimidine
• Synonyms: 2-(4-fluorophenyl)-7-methylimidazo[1,2-a]pyrimidine
• CAS NO: 955-75-9
• Molecular Weight: 227.241
• Mol File: 955-75-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(4-fluorophenyl)-7-methylimidazo[1,2-a]pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-fluorophenyl)-7-methylimidazo[1,2-a]pyrimidine(955-75-9)
• EPA Substance Registry System: 2-(4-fluorophenyl)-7-methylimidazo[1,2-a]pyrimidine(955-75-9)

Safety Data

• Hazardous Substances Data: 955-75-9(Hazardous Substances Data)

Upstream product

• 108-52-1 4-Methyl-pyrimidin-2-ylamin 
• 403-29-2 2-bromo-4'-fluoroacetophenone 

Relevant articles and documents

Synthesis and characterization of novel classes of PDE10A inhibitors - 1H-1,3-benzodiazoles and imidazo[1,2-a]pyrimidines

New compounds containing [1,2,4]triazolo [1,5-a]pyridine (I), pyrazolo [1,5-a]pyridine (II), 1H-1,3-benzodiazole (III) and imidazo [1,2-a]pyrimidine (IV) backbones were designed and synthesized for PDE10A interaction. Among these compounds, 1H-1,3-benzodiazoles and imidazo [1,2-a]pyrimidines showed the highest affinity for PDE10A enzyme as well as good metabolic stability. Both classes of compounds were identified as selective and potent PDE10A enzyme inhibitors.