95524-19-9 Usage
Description
2-TRIFLUOROMETHYLCYCLOPENTANONE, also known as 2-trifluoromethylcyclopentanone, is a chemical compound with the molecular formula C6H7F3O. It is a cyclic ketone with a trifluoromethyl group attached to a cyclopentane ring. 2-TRIFLUOROMETHYLCYCLOPENTANONE is characterized by its unique structure and chemical reactivity, making it a valuable building block in organic synthesis and pharmaceutical research. It is a volatile, colorless liquid with a distinctive odor and should be handled with care due to its potential health hazards and flammability.
Uses
Used in Organic Synthesis:
2-TRIFLUOROMETHYLCYCLOPENTANONE is used as a building block in organic synthesis for its unique structure and chemical reactivity. It allows for the creation of various complex organic molecules and contributes to the development of new compounds with potential applications in various fields.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 2-TRIFLUOROMETHYLCYCLOPENTANONE is used as a key intermediate in the development of new drugs. Its unique properties enable the synthesis of novel drug candidates with potential therapeutic benefits. Researchers leverage its reactivity to design and synthesize innovative pharmaceutical agents that address unmet medical needs.
Used in Material Science:
2-TRIFLUOROMETHYLCYCLOPENTANONE also finds applications in material science, where it is utilized in the development of new materials with specific properties. Its unique structure and reactivity allow for the creation of advanced materials with potential uses in various industries, such as electronics, coatings, and adhesives.
Check Digit Verification of cas no
The CAS Registry Mumber 95524-19-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,5,5,2 and 4 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 95524-19:
(7*9)+(6*5)+(5*5)+(4*2)+(3*4)+(2*1)+(1*9)=149
149 % 10 = 9
So 95524-19-9 is a valid CAS Registry Number.
95524-19-9Relevant articles and documents
Electrochemical Synthesis of Fluorinated Ketones from Enol Acetates and Sodium Perfluoroalkyl Sulfinates
Vil’, Vera A.,Merkulova, Valentina M.,Ilovaisky, Alexey I.,Paveliev, Stanislav A.,Nikishin, Gennady I.,Terent’ev, Alexander O.
supporting information, p. 5107 - 5112 (2021/06/30)
The electrochemical synthesis of fluorinated ketones from enol acetates and RfSO2Na in an undivided cell under constant current conditions was developed. The electrosynthesis proceeded via perfluoroalkyl radical generation from sodium perfluoroalkyl sulfinate followed by addition to the enol acetate and transformation of the resulting C radical to a fluorinated ketone. The method is applicable to a wide range of enol acetates and results in the desired products in yields of 20 to 85%.
Radical Desulfur-Fragmentation and Reconstruction of Enol Triflates: Facile Access to α-Trifluoromethyl Ketones
Su, Xiaolong,Huang, Honggui,Yuan, Yaofeng,Li, Yi
supporting information, p. 1338 - 1341 (2017/01/24)
We report an efficient oxidative radical desulfur-fragmentation and reconstruction of enol triflates for the synthesis of α-CF3ketones. Preliminary mechanistic studies disclosed that oxidative fragmentation to release a CF3radical fr
Zincate-type enolate for radical α-trifluoromethylation
Tomita, Yuichi,Ichikawa, Yoshiyuki,Itoh, Yoshimitsu,Kawada, Kosuke,Mikami, Koichi
, p. 8922 - 8925 (2008/03/14)
Ketone zincate-type enolates can be applied to radical trifluoromethylation for the general synthesis of α-CF3-ketones, cyclopentanones in particular. The addition of diethylzinc to lithium enolates is the key in the preparation of the zincate-
