95648-78-5

Basic information

• Product Name: 2'-Deoxythymidine-5'-diphosphate trisodium salt
• Synonyms: THYMIDINE 5'-DIPHOSPHATE SODIUM SALT;THYMIDINE-5'-DIPHOSPHATE TRISODIUM SALT;5'-DTDP-NA3;2'-DEOXYTHYMIDINE 5'-DIPHOSPHATE TRISODIUM SALT;Thymidine 5'-(trihydrogen diphosphate), trisodium salt;1-(1-thyminyl)-2-deoxy-β-d-ribofuranose-5-diphosphate trisodium salt;2''-DEOXYTHMIDINE-5''-DIPHOSPHATE, TRISODIUM SALT(DTDP.NA3);2''-DEOXYTHYMIDINE-5''-DIPHOSPHATE, TRISODIUM SALT (DTDP.NA3)
• CAS NO: 95648-78-5
• Molecular Formula: C10H13N2Na3O12P2
• Molecular Weight: 484.13
• EINECS: 306-019-3
• Mol File: 95648-78-5.mol
• Article Data: 0

Chemical Properties

• Appearance: White/Powder
• Storage Temp.: −20°C
• Water Solubility: Soluble in water.
• CAS DataBase Reference: 2'-Deoxythymidine-5'-diphosphate trisodium salt(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-Deoxythymidine-5'-diphosphate trisodium salt(95648-78-5)
• EPA Substance Registry System: 2'-Deoxythymidine-5'-diphosphate trisodium salt(95648-78-5)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22-68/20/21/22
• Safety Statements: 22-36/37
• WGK Germany: 3
• F: 10-21
• Hazardous Substances Data: 95648-78-5(Hazardous Substances Data)

Usage

Description

2'-Deoxythymidine-5'-diphosphate trisodium salt, also known as dTDP, is a synthetic nucleotide that plays a crucial role in various molecular biology applications. It is a modified form of thymidine diphosphate with a trisodium salt group, which enhances its stability and solubility in aqueous solutions. This modification allows for better performance in laboratory settings and ensures consistent results in experiments.

Uses

Used in Molecular Biology Applications:
2'-Deoxythymidine-5'-diphosphate trisodium salt is used as a stable nucleotide for PCR (Polymerase Chain Reaction) and RT-PCR (Reverse Transcription Polymerase Chain Reaction) processes. Its stability and solubility make it an ideal choice for these applications, as it ensures accurate amplification of DNA or cDNA sequences and reduces the risk of errors during the reaction.
In PCR, dTDP serves as a building block for the synthesis of new DNA strands, while in RT-PCR, it is used to generate cDNA from RNA templates. The use of dTDP in these techniques allows researchers to study gene expression, identify genetic variations, and develop diagnostic tools for various diseases.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2'-Deoxythymidine-5'-diphosphate trisodium salt is used as an intermediate in the synthesis of nucleotide analogs and other therapeutic agents. These analogs can be used to develop antiviral and anticancer drugs, as they can interfere with the replication of viral or cancerous cells, thus inhibiting their growth and spread.
Used in Research and Development:
2'-Deoxythymidine-5'-diphosphate trisodium salt is also used in research and development for the study of nucleotide metabolism, DNA repair mechanisms, and the development of novel molecular biology techniques. Its stable nature and solubility make it a valuable tool for scientists working in these fields, as it allows for more accurate and reliable experimental results.