96081-16-2

Basic information

• Product Name: HUMAN IGF-II
• Synonyms: INSULIN-LIKE GROWTH FACTOR-II;INSULIN-LIKE GROWTH FACTOR-II HUMAN;INSULIN-LIKE GROWTH FACTOR-II, HUMAN, RECOMBINANT;IGF-II, HUMAN;IGF-2 HUMAN;IGF-II;HUMAN INSULIN-LIKE GROWTH FACTOR II;HUMAN IGF-II
• CAS NO: 96081-16-2
• Molecular Formula: C24H36N4O9
• Molecular Weight: 524.56404
• Mol File: 96081-16-2.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: -15°C
• CAS DataBase Reference: HUMAN IGF-II(CAS DataBase Reference)
• NIST Chemistry Reference: HUMAN IGF-II(96081-16-2)
• EPA Substance Registry System: HUMAN IGF-II(96081-16-2)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 96081-16-2(Hazardous Substances Data)

Usage

Biochem/physiol Actions

Insulin-like growth factor II (IGF-II) also known as multiplication stimulating activity (MSA), shows virtually identical bioactivities as IGF-I. Expression of IGF-II is highest in fetal tissues, where it is believed to play a major role in overall growth and development. After birth IGF-II expression decreases to much lower levels in a variety of tissues. IGF-II is produced also in several tumors. IGF-II binds to IGF-II receptor (IGF-IIR), to IGF-IR and weakly to the insulin receptor (IR). All IGF-II bioactivities in adult tissues are generally attributed to its interaction with IGF-IR. However, during embryogenesis the roles of both IGF-IIR and IR may be significant in promoting normal growth.