96159-88-5

Basic information

• Product Name: 2-(3-nitrophenyl)-4,5-dihydro-1,3-thiazole
• Synonyms: 2-{3-nitrophenyl}-4,5-dihydro-1,3-thiazole
• CAS NO: 96159-88-5
• Molecular Formula: C₉H₈N₂O₂S
• Molecular Weight: 208.237
• Mol File: 96159-88-5.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 365°Cat760mmHg
• Flash Point: 174.6°C
• Appearance: /
• Density: 1.43g/cm³
• Vapor Pressure: 3.39E-05mmHg at 25°C
• Refractive Index: 1.69
• CAS DataBase Reference: 2-(3-nitrophenyl)-4,5-dihydro-1,3-thiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-nitrophenyl)-4,5-dihydro-1,3-thiazole(96159-88-5)
• EPA Substance Registry System: 2-(3-nitrophenyl)-4,5-dihydro-1,3-thiazole(96159-88-5)

Safety Data

• Hazardous Substances Data: 96159-88-5(Hazardous Substances Data)

Usage

Heterocyclic compound

Contains a thiazole ring (five-membered ring with sulfur and nitrogen atoms)

Contains a nitrophenyl group

Benzene ring with a nitro group attached

Used in pharmaceutical industry

As a building block for creating compounds with potential medicinal properties

Potential as an antitumor agent

Has been studied for its ability to inhibit certain enzymes

Potential application in materials science

Investigated for use in the development of fluorescent materials

InChI:InChI=1/C9H8N2O2S/c12-11(13)8-3-1-2-7(6-8)9-10-4-5-14-9/h1-3,6H,4-5H2

Upstream product

• 2722-34-1 2-phenylthiazoline 
• 60-23-1 Cysteamine 
• 619-24-9 3-nitrobenzonitrile 
• 70102-34-0 3-nitrothiobenzamide 
• 2576-47-8 2-bromoethylamine hydrobromide 
• 3431-62-7 3-nitrobenzaldoxime 

Relevant articles and documents

A single-reagent-driven multistep one-pot preparation of thiazolines and 1,3-thiazines from aldoximes, nitriles, and carboxylic acids

N-(ω-Bromoalkyl)dichlorothiophosphoramidates have been designed as a new class of reagent for the single-reagent-driven multistep preparation of 2-substituted thiazolines and 1,3-thiazines from ald-oximes, nitriles, or carboxylic acids. A wide range of substrates both aromatic as well as aliphatic were investigated and found suitable for the developed protocol.

One-pot synthesis of 2-arylthiazolines with 1-butyl-3-methylimidazolium tribromide as a catalytic reagent

A simple, inexpensive, and efficient one-pot synthesis of 2-arylthiazoline derivatives under solvent-free conditions using a catalytic amount of 1-butyl-3-methylimidazolium tribromide with excellent product yields is reported. This methodology provides ea

Easy access to thiazolines and thiazines via tandem S-alkylation- cyclodeamination of thioamides/haloamines

This is the first report of a facile synthesis of thiazolines and thiazines from a self-catalyzed, water assisted tandem S-alkylation-cyclodeamination reaction of thioamides/haloamines. The reaction is clean and efficient with simple product work-up, and is applicable to a variety of substrates.