96962-78-6Relevant articles and documents
Facile synthesis of 3-(trifluoromethyl)adamantane derivatives
Zhyhadlo, Yevheniia Y.,Gaidai, Alexander V.,Levandovskiy, Igor A.,Bezdudny, Andriy V.,Rassukana, Yuliya V.
, p. 11 - 14 (2017)
A facile synthesis for 1-fluoro-3-(trifluoromethyl)adamantane, based on fluorination of 3-hydroxyadamantane-1-carboxylic acid, was developed. Its synthetic potentialities for preparation of (trifluoromethyl)adamantane derivatives containing diverse functional groups (acids, amines, etc.) in a bridgehead position, were disclosed.