97111-56-3

Basic information

• Product Name: 4-Chloro-1-(4-methoxy-phenyl)-[1,2,4]triazolo[4,3-a]quinoxaline
• Synonyms: 4-Chloro-1-(4-methoxy-phenyl)-[1,2,4]triazolo[4,3-a]quinoxaline
• CAS NO: 97111-56-3
• Molecular Weight: 310.743
• Mol File: 97111-56-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-Chloro-1-(4-methoxy-phenyl)-[1,2,4]triazolo[4,3-a]quinoxaline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Chloro-1-(4-methoxy-phenyl)-[1,2,4]triazolo[4,3-a]quinoxaline(97111-56-3)
• EPA Substance Registry System: 4-Chloro-1-(4-methoxy-phenyl)-[1,2,4]triazolo[4,3-a]quinoxaline(97111-56-3)

Safety Data

• Hazardous Substances Data: 97111-56-3(Hazardous Substances Data)

Upstream product

• 97111-46-1 C₂₅H₂₃ClN₆O 
• 97111-30-3 C₂₆H₂₅ClN₆O 
• 97111-33-6 C₂₂H₁₆ClN₇O₃ 
• 97111-29-0 C₂₄H₂₂ClN₇O 
• 97111-39-2 4-methoxybenzaldehyde (3-chloro-2-quinoxalyl)hydrazone 
• 51347-93-4 2‐chloro‐3‐hydrazinylquinoxaline 
• 95-54-5 1,2-diamino-benzene 
• 15804-19-0 quinoxaline-2,3-dione 
• 2213-63-0 2,3-dichloroquinoxaline 
• 97111-32-5 C₂₂H₁₆ClN₇O₃ 
• 97111-31-4 C₂₂H₁₇ClN₆O 
• 97111-50-7 C₂₂H₁₆ClN₇O₃ 

Relevant articles and documents

Studies in the syntheses of s-triazolo[4,3-a] quinoxalines

o-Phenylendiamine 1 is condensed with oxalic acid using Phillip's procedure to obtain quinoxaline-2,3-doine 2, which on treatment with POCl3 gives the known 2,3-dichloroquinoxaline 3. 2-Chloro-3-hydrazinoquinoxaline 4 is prepared in a facile and simple way by treatment of 3 with hydrazine hydrate in methanol or in dioxane containing triethylamine. Condensation of 4 with a variety of aldehydes in DMF at room temperature furnishes the corresponding arylidene/alkylidine derivatives 5 which undergo smooth nucleophilic substitutions of chlorine by alkoxide or phenoxide ions yielding 2-alkoxy/phenoxy-3-(2-arylidene/alkylidene hydrazino) quinoxalines 6. The dehydrogenative cyclisation of 6 is achieved with chloranil in refluxing 1,2- dichloroethane resulting in s-triazole-[4,3-a] quinoxalines 7 whose structures are supported by spectral and analytical data and by alternate chemical synthesis in the case of the parent compound 7a.