97210-23-6

Basic information

• Product Name: (±)-1-(4-chlorophenyl)-2-(1H-pyrrol-1-yl)ethanol
• Synonyms: (±)-1-(4-chlorophenyl)-2-(1H-pyrrol-1-yl)ethanol
• CAS NO: 97210-23-6
• Molecular Weight: 221.686
• Mol File: 97210-23-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (±)-1-(4-chlorophenyl)-2-(1H-pyrrol-1-yl)ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: (±)-1-(4-chlorophenyl)-2-(1H-pyrrol-1-yl)ethanol(97210-23-6)
• EPA Substance Registry System: (±)-1-(4-chlorophenyl)-2-(1H-pyrrol-1-yl)ethanol(97210-23-6)

Safety Data

• Hazardous Substances Data: 97210-23-6(Hazardous Substances Data)

Upstream product

• 5467-71-0 4-chlorophenacylamine hydrochloride 
• 97090-93-2 1-(4-chlorophenyl)-2-(1H-pyrrol-1-yl)ethan-1-one 

Downstream Products

• 97090-86-3 1-[2-(2-Chloro-benzyloxy)-2-(4-chloro-phenyl)-ethyl]-1H-pyrrole 
• 97090-87-4 1-[2-(4-Chloro-benzyloxy)-2-(4-chloro-phenyl)-ethyl]-1H-pyrrole 

Relevant articles and documents

Discovery of in vitro antitubercular agents through in silico ligand-based approaches

The development of new anti-tubercular agents represents a constant challenge mostly due to the insurgency of resistance to the currently available drugs. In this study, a set of 60 molecules were selected by screening the Asinex and the ZINC collections and an in house library by means of in silico ligand-based approaches. Biological assays in Mycobacterium tuberculosis H37Ra ATCC 25177 strain highlighted (±)-1-(4-chlorophenyl)-2-(1H-imidazol-1-yl)ethyl-4-(3,4-dichlorophenyl)piperazine-1-carboxylate (5i) and 3-(4-chlorophenyl)-5-(2,4-dimethylpyrimidin-5-yl)-2-methylpyrazolo[1.5-a]pyrimidin-7(4H)-one (42) as the most potent compounds, having a Minimum Inhibitory Concentration (MIC) of 4 and 2 μg/4g/mL respectively. These molecules represent a good starting point for further optimization of effective anti-TB agents.