97484-73-6

Basic information

• Product Name: 1-benzyl-1H-pyrido[2,3-d][1,3]oxazine-2,4-dione
• Synonyms: 1-benzyl-1H-pyrido[2,3-d][1,3]oxazine-2,4-dione
• CAS NO: 97484-73-6
• Molecular Formula: C₁₄H₁₀N₂O₃
• Molecular Weight: 254.2408
• Mol File: 97484-73-6.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 446.056°C at 760 mmHg
• Flash Point: 223.567°C
• Appearance: /
• Density: 1.39g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.648
• CAS DataBase Reference: 1-benzyl-1H-pyrido[2,3-d][1,3]oxazine-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl-1H-pyrido[2,3-d][1,3]oxazine-2,4-dione(97484-73-6)
• EPA Substance Registry System: 1-benzyl-1H-pyrido[2,3-d][1,3]oxazine-2,4-dione(97484-73-6)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 97484-73-6(Hazardous Substances Data)

Usage

General Description

1-benzyl-1H-pyrido[2,3-d][1,3]oxazine-2,4-dione is a chemical compound with potential pharmaceutical applications. It is a heterocyclic compound that contains a benzyl group and a pyrido-oxazine ring system. 1-benzyl-1H-pyrido[2,3-d][1,3]oxazine-2,4-dione has been studied for its potential as an antiviral and antitumor agent. Its structure and properties make it a promising candidate for further research and development in the field of medicinal chemistry. However, further studies are needed to fully understand its pharmacological potential and possible therapeutic applications.

InChI:InChI=1/C14H10N2O3/c17-13-11-7-4-8-15-12(11)16(14(18)19-13)9-10-5-2-1-3-6-10/h1-8H,9H2

Upstream product

• 100-44-7 benzyl chloride 
• 21038-63-1 3-azaisatoic anhydride 
• 5860-70-8 2-Aminocarbonylnicotinic acid 
• 33522-80-4 2-(benzylamino)nicotinic acid 
• 503-38-8 trichloromethyl chloroformate 
• 100-39-0 benzyl bromide 

Downstream Products

• 97484-86-1 2,3-dihydro-10-phenylmethylimidazo<1,2-a>pyrido<2,3-d>pyrimidin-5(10H)-one 
• 111396-18-0 1-(2'-benzylamino-3'-pyridinyl) cyclopentanol 
• 111396-26-0 1-(2'-benzylamino-3'-pyridinyl) cyclohexanol 
• 686263-53-6 1-benzyl-3-(1,1-dioxido-4H-1,2,4-benzothiadiazin-3-yl)-4-hydroxy-1,8-naphthyridin-2(1H)-one 
• 179064-00-7 1-benzyl-4-hydroxy-2-oxo-1,2-dihydro[1,8]naphthyridine-3-carboxylic acid ethyl ester 
• 686268-57-5 1-benzyl-4-hydroxy-3-(6-methoxy-1, 1-dioxido-4H-1,2,4-benzothiadiazin-3-yl)-1,8-naphthyridin-2(1H)-one 
• 686268-38-2 1-Benzyl-4-hydroxy-3-(5-methoxy-1,1-dioxido-4H-1,2,4-benzothiadiazin-3-yl)-1,8-naphthyridin-2(1H)-one 
• 686265-76-9 1-benzyl-3-(5-bromo-1,1-dioxido-4H-1,2,4-benzothiadiazin-3-yl)-4-hydroxy-1,8-naphthyridin-2(1H)-one 
• 686262-92-0 1-butyl-3-(1,1-dioxido-4H-1,2,4-benzothiadiazin-3-yl)-4-hydroxy-1,8-naphthyridin-2(1H)-one 
• 686268-60-0 N-[3-(1-benzyl-4-hydroxy-2-oxo-1,2-dihydro-1,8-naphthyridin-3-yl)-1,1-dioxido-4H-1,2,4-benzothiadiazin-6-yl]acetamide 
• 686268-65-5 1-benzyl-4-hydroxy-3-(8-methyl-1,1-dioxido-4H-1,2,4-benzothiadiazin-3-yl)-1,8-naphthyridin-2(1H)-one 
• 686266-01-3 ethyl 1-benzyl-4-hydroxy-5-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylate 
• 847776-02-7 1-benzyl-4-hydroxy-3-(methylsulfonyl)[1,8]naphthyridin-2(1H)-one 
• 847776-10-7 (E) 1-benzyl-4-hydroxy-3-nitro-pyrido[2,3-b]pyridine-2(1H)-one 

Relevant articles and documents

SUBSTITUTED NAPHTHYRIDINE DERIVATIVES AS INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR AND THEIR USE IN THE TREATMENT OF HUMAN DISEASES

Inhibitors of MIF having a naphthyridine backbone are provided which have utility in the treatment of a variety of disorders, including the treatment of pathological conditions associated with MIF activity. The inhibitors of MIF have the following structures: (Ia), (Ib), (Ic), (Id) including stereoisomers, prodrugs and pharmaceutically acceptable salts thereof, wherein n, R, R1, R2, X, Y and Z are as defined herein. Compositions containing an inhibitor of MIF in combination with a pharmaceutically acceptable carrier are also provided, as well as methods for use of the same.

Anti-infective agents

Compounds having the formula are hepatitis C (HCV) polymerase inhibitors. Also disclosed are a composition and method for inhibiting hepatitis C (HCV) polymerase, processes for making the compounds, and synthetic intermediates employed in the processes.

REACTIONS OF αω-BIS(BROMOMAGNESIO)ALKANES WITH HETEROCYCLIC ANHYDRIDES. A NOVEL SYNTHESIS OF FIVE AND SIX-MEMBERED 1-(o-AMINOPHENYL)CYCLOALKANOLS AND 1-(2'-AMINO-3'-PYRIDINYL)CYCLOALKANOLS

Isatoic anhydrides and azaisatoic anhydrides are converted by reaction with 1,4-bis(bromomagnesio)butane and 1,5-bis(bromomagnesio)pentane into the corresponding 1-(o-aminophenyl)cycloalkanols and 1-(2'-amino-3'pyridinyl)cycloalcanols.