97641-59-3

Basic information

• Product Name: L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-L-isoleucyl-, methyl ester
• CAS NO: 97641-59-3
• Molecular Formula: C21H32N2O5
• Molecular Weight: 392.495
• Mol File: 97641-59-3.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-L-isoleucyl-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-L-isoleucyl-, methyl ester(97641-59-3)
• EPA Substance Registry System: L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-L-isoleucyl-, methyl ester(97641-59-3)

Safety Data

• Hazardous Substances Data: 97641-59-3(Hazardous Substances Data)

Upstream product

• 13139-16-7 N-(tert-butyloxycarbonyl)-L-isoleucine 
• 2577-90-4 methyl (2S)-2-amino-3-phenylpropanoate 
• 7524-50-7 methyl (2S)-2-amino-3-phenylpropanoate hydrochloride 

Downstream Products

• 103372-21-0 (S)-2-[(2S,3S)-2-((3S,4S)-4-tert-Butoxycarbonylamino-3-hydroxy-6-methyl-heptanoylamino)-3-methyl-pentanoylamino]-3-phenyl-propionic acid methyl ester 
• 215512-41-7 (S)-2-[(2S,3S)-2-(2-Benzyloxyamino-acetylamino)-3-methyl-pentanoylamino]-3-phenyl-propionic acid methyl ester 
• 215512-42-8 (S)-2-((2S,3S)-2-{2-[Benzyloxy-((S)-2-tert-butoxycarbonylamino-3-phenyl-propionyl)-amino]-acetylamino}-3-methyl-pentanoylamino)-3-phenyl-propionic acid methyl ester 
• 112374-78-4 C₆₈H₈₇N₉O₁₄S 
• 103372-22-1 (S)-2-[(2S,3S)-2-((3S,4S)-4-{(S)-2-tert-Butoxycarbonylamino-3-[1-(toluene-4-sulfonyl)-1H-imidazol-4-yl]-propionylamino}-3-hydroxy-6-methyl-heptanoylamino)-3-methyl-pentanoylamino]-3-phenyl-propionic acid methyl ester 
• 103352-62-1 C₄₉H₇₁N₇O₁₀ 
• 112374-69-3 C₅₆H₇₇N₇O₁₂S 
• 112374-71-7 C₅₈H₇₅N₉O₁₁ 
• 112374-70-6 C₆₁H₈₁N₉O₁₂ 
• 137150-41-5 N-(tert-butoxycarbonyl)prolylisoleucinylphenylalanine methyl ester 
• 75286-42-9 Boc-Ile-Phe-OH 

Relevant articles and documents

Role of side-chain and chirality of the amino acids on the supramolecular assemblies of dipeptides

The supramolecular self-association of alternating L/L and L/D amino acid-containing dipeptides, Boc-L-Ile-L-Phe-OMe (1), Boc-L-Ile-D-Phe-OMe (2), Boc-L-Ile-L-Phg-OMe (3, Phg = phenylglycine), and Boc-L-Ile-D-Phg-OMe (4) have been investigated. The presence of extra methylene (-CH2-) group on the side-chain of C-terminal Phe-of 1 causes a significant deviation of molecular arrangements from that of 3. While the molecules in 1 self-assemble to form a single helix-like architecture, the molecules in 3 self-associate around a water molecule to form a cylinder-like structure in the crystalline state. Alternatively, the observed supramolecular arrangements of 2 and 4 are similar, but deviate from that of 1 and 3, due to chirality difference. Peptides 2 and 4 exhibit a discontinued double helix-like structure in the crystalline state. While 1 and 3 self-associate to form helical ribbon-like and nano tube-like structures, respectively, both 2 and 4 form nano rod-like structures in solution.

Pd-Catalyzed Site-Selective C(sp2)-H Olefination and Alkynylation of Phenylalanine Residues in Peptides

Pd-catalyzed site-selective C(sp2)-H olefination and alkynylation of phenylalanine residues in peptides are described. The amino acids within the peptides are used as native bidentate directing groups to facilitate C-H functionalization. This p

Pd-catalyzed intramolecular C(sp2)-H amination of phenylalanine moieties in dipeptides: Synthesis of indoline-2-carboxylate-containing dipeptides

A palladium-catalyzed intramolecular C(sp2)-H amination of phenylalanine moieties in dipeptides is described. By this protocol, a series of indoline-2-carboxylate-containing dipeptides were synthesized from dipeptides. The N-protected amino aci