97760-94-6

Basic information

• Product Name: 2-FLUORO-4-IODOACETANILIDE
• Synonyms: 2-FLUORO-4-IODOACETANILIDE;N-(2-Fluoro-4-iodophenyl)acetamide;N-(2-Fluoro-4-iodophenyl)acetamide, N-(2-Fluoro-4-iodophenyl)ethanamide
• CAS NO: 97760-94-6
• Molecular Formula: C₈H₇FINO
• Molecular Weight: 279.05
• Product Categories: Amines;blocks;FluoroCompounds;Iodides
• Mol File: 97760-94-6.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 348.3°C at 760 mmHg
• Flash Point: 164.4°C
• Appearance: /
• Density: 1.875g/cm³
• Vapor Pressure: 5.09E-05mmHg at 25°C
• Refractive Index: 1.637
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-FLUORO-4-IODOACETANILIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-FLUORO-4-IODOACETANILIDE(97760-94-6)
• EPA Substance Registry System: 2-FLUORO-4-IODOACETANILIDE(97760-94-6)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 97760-94-6(Hazardous Substances Data)

Usage

General Description

2-Fluoro-4-iodoacetanilide is a chemical compound that belongs to the class of acetanilides, which are organic compounds derived from acetanilide. It consists of a fluorine atom and an iodine atom attached to a benzene ring, as well as an acetyl group. 2-FLUORO-4-IODOACETANILIDE is often used in pharmaceutical research and drug development due to its potential applications in the synthesis of various drugs and pharmaceuticals. It may have properties that make it useful as a building block in the creation of novel compounds with therapeutic potential. The specific characteristics and uses of this compound can vary depending on its intended application and the specific research or development goals.

InChI:InChI=1/C8H7FINO/c1-5(12)11-8-3-2-6(10)4-7(8)9/h2-4H,1H3,(H,11,12)

Upstream product

• 29632-74-4 2-fluro-4-iodoaniline 
• 108-24-7 acetic anhydride 
• 326-66-9 N-(4-bromo-2-fluorophenyl)acetamide 
• 75-36-5 acetyl chloride 
• 348-54-9 2-Fluoroaniline 

Downstream Products

• 93129-68-1 4-acetylamino-3-fluoro-benzonitrile 
• 97776-40-4 1-(4-Amino-3-fluoro-phenyl)-2-ethylamino-ethanol 
• 56795-45-0 4'-amino-3'-cyano-5'-fluoro-acetophenone 
• 54238-83-4 1-(4-Amino-3-chloro-5-fluoro-phenyl)-2-ethylamino-ethanone 
• 740030-01-7 1-(4-Amino-3-bromo-5-fluoro-phenyl)-2-ethylamino-ethanone 
• 56340-17-1 4'-amino-2-tert-butylamino-3'-fluoro-5'-iodo-acetophenone 
• 783246-62-8 1-(4-Amino-3-bromo-5-fluoro-phenyl)-2-(1,1-dimethyl-propylamino)-ethanone 
• 97776-43-7 1-(4-Amino-3-chloro-5-fluoro-phenyl)-2-ethylamino-ethanol 
• 97776-45-9 1-(4-Amino-3-bromo-5-fluoro-phenyl)-2-ethylamino-ethanol 
• 95656-56-7 1-(4'-Amino-3'-fluoro-5'-iodo-phenyl)-2-tert-butylamino-ethanol 
• 97776-50-6 1-(4'-Amino-3'-bromo-5'-fluoro-phenyl)-2-tert-pentylamino-ethanol 
• 54240-25-4 4'-amino-3'-bromo-2-cyclopropylamino-5'-fluoro-acetophenone 
• 745725-51-3 1-(4-Amino-3-bromo-5-fluoro-phenyl)-2-(2-hydroxy-1,1-dimethyl-ethylamino)-ethanone 
• 56340-21-7 2-Amino-5-(2-ethylamino-acetyl)-3-fluoro-benzonitrile 

Relevant articles and documents

Novel potent antagonists of transient receptor potential channel, vanilloid subfamily member 1: Structure-activity relationship of 1,3-diarylalkyl thioureas possessing new vanilloid equivalents

Recently, 1,3-diarylalkyl thioureas have merged as one of the promising nonvanilloid TRPV1 antagonists possessing excellent therapeutic potential in pain regulation. In this paper, the full structure-activity relationship for TRPV1 antagonism of a novel series of 1,3-diarylalky thioureas is reported. Exploration of the structure-activity relationship, by systemically modulating three essential pharmacophoric regions, led to six examples of 1,3-dibenzyl thioureas, which exhibit Ca2+ uptake inhibition in rat DRG neuron with IC50 between 10 and 100 nM.

Tetrazolyl-phenyl acetamide glucokinase activators

Tetrazolyl-phenyl acetamides are active as glucokinase activators, and are able to increase insulin secretion, which makes them useful for treating type II diabetes.

Tetrazolyl-phenyl acetamide glucokinase activators

Tetrazolyl-phenyl acetamides are active as glucokinase activators, and are able to increase insulin secretion, which makes them useful for treating type II diabetes.