97792-39-7 Usage
Description
Z-GLY-GLY-LEU-AMC, also known as Z-GGL-AMC, is a synthetic peptide substrate that is widely used in the study of proteolytic enzymes. It consists of a series of amino acids, including glycine, glycine, leucine, and a 7-amino-4-methylcoumarin (AMC) group. The AMC group serves as a fluorophore, allowing for the detection and quantification of enzymatic activity.
Uses
Used in Research Applications:
Z-GLY-GLY-LEU-AMC is used as a fluorogenic substrate for studying the activity of proteolytic enzymes, particularly the chymotrypsin-like activity of the 20S proteasome. It is a sensitive and reliable tool for monitoring enzymatic activity in various experimental settings.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Z-GLY-GLY-LEU-AMC is used as a screening tool for the development of new drugs targeting proteolytic enzymes. By monitoring the activity of these enzymes in the presence of potential drug candidates, researchers can identify compounds with inhibitory or activating effects on enzyme function.
Used in Diagnostic Applications:
Z-GLY-GLY-LEU-AMC can be employed as a diagnostic tool for detecting and monitoring the activity of proteolytic enzymes in various diseases, such as cancer and neurodegenerative disorders. Abnormal enzyme activity can be indicative of disease progression or response to treatment, making Z-GLY-GLY-LEU-AMC a valuable diagnostic aid.
Used in Quality Control:
In the biotechnology and pharmaceutical industries, Z-GLY-GLY-LEU-AMC is used as a quality control standard to ensure the purity and activity of proteolytic enzymes in commercial enzyme preparations. By comparing the activity of these enzymes with the known activity of Z-GLY-GLY-LEU-AMC, manufacturers can ensure the consistency and reliability of their products.
Check Digit Verification of cas no
The CAS Registry Mumber 97792-39-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,7,7,9 and 2 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 97792-39:
(7*9)+(6*7)+(5*7)+(4*9)+(3*2)+(2*3)+(1*9)=197
197 % 10 = 7
So 97792-39-7 is a valid CAS Registry Number.
InChI:InChI=1/C28H32N4O7/c1-4-17(2)26(27(36)31-20-10-11-21-18(3)12-25(35)39-22(21)13-20)32-24(34)15-29-23(33)14-30-28(37)38-16-19-8-6-5-7-9-19/h5-13,17,26H,4,14-16H2,1-3H3,(H,29,33)(H,30,37)(H,31,36)(H,32,34)
