97952-36-8

Basic information

• Product Name: GUANOSINE 5'-O-(2-THIODIPHOSPHATE) TRILITHIUM SALT
• Synonyms: GDP-BETA-S TRILITHIUM SALT;GDP-BETA-S 3LI;GDP-BETA-S TRILITHIUM;GDP-BETA-S-LI3;GUANOSINE 5'-[BETA-THIO]DIPHOSPHATE TRILITHIUM SALT;GUANOSINE-5'-O-(2-THIODIPHOSPHATE) TRILITHIUM;GUANOSINE-5'-O-(2-THIODIPHOSPHORIC ACID), TRILITHIUM;GUANOSINE 5'-O-(2-THIODIPHOSPHATE) TRILITHIUM SALT
• CAS NO: 97952-36-8
• Molecular Formula: C10H12Li3N5O10P2S
• Molecular Weight: 477.07
• EINECS: 308-328-9
• Mol File: 97952-36-8.mol
• Article Data: 0

Chemical Properties

• Appearance: white/
• Storage Temp.: −20°C
• Solubility: H2O: soluble20mg/mL (Solutions are very unstable; prepare immedi
• BRN: 8181243
• CAS DataBase Reference: GUANOSINE 5'-O-(2-THIODIPHOSPHATE) TRILITHIUM SALT(CAS DataBase Reference)
• NIST Chemistry Reference: GUANOSINE 5'-O-(2-THIODIPHOSPHATE) TRILITHIUM SALT(97952-36-8)
• EPA Substance Registry System: GUANOSINE 5'-O-(2-THIODIPHOSPHATE) TRILITHIUM SALT(97952-36-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• F: 3-10-21
• Hazardous Substances Data: 97952-36-8(Hazardous Substances Data)

Usage

Description

GUANOSINE 5'-O-(2-THIODIPHOSPHATE) TRILITHIUM SALT is a chemical compound that functions as an inhibitor of G-protein activation. It is utilized in various research applications to understand the role of G-proteins in cellular processes and signal transduction pathways.

Uses

Used in Neuroscience Research:
GUANOSINE 5'-O-(2-THIODIPHOSPHATE) TRILITHIUM SALT is used as a research tool for studying the effects of G-protein inhibition on acetylcholine current in bag cell neurons. This helps researchers to gain insights into the underlying mechanisms of neuronal signaling and neurotransmission.
Used in Cellular Signaling Studies:
GUANOSINE 5'-O-(2-THIODIPHOSPHATE) TRILITHIUM SALT is employed as an inhibitor to investigate the role of G-proteins in cholinergic-dependent plateau potentials. This application aids in understanding the complex interactions between G-proteins and other cellular components in the context of signal transduction.

Biochem/physiol Actions

Guanosine 5′-[β-thio]diphosphate is a non-hydrolyzable analog of guanosine. It functions as an inhibitor of G-protein activation.