97966-31-9

Basic information

• Product Name: Methyl 3-ethoxy-4-Methoxybenzoate
• Synonyms: Methyl 3-ethoxy-4-Methoxybenzoate;methyl 3-ethoxy-4-methoxybenzoate(WX192030)
• CAS NO: 97966-31-9
• Molecular Formula: C₁₁H₁₄O₄
• Molecular Weight: 210.22646
• Mol File: 97966-31-9.mol
• Article Data: 10

Chemical Properties

• Melting Point: 81-83 °C
• Boiling Point: 300.1±22.0 °C(Predicted)
• Appearance: /
• Density: 1.095±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Methyl 3-ethoxy-4-Methoxybenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 3-ethoxy-4-Methoxybenzoate(97966-31-9)
• EPA Substance Registry System: Methyl 3-ethoxy-4-Methoxybenzoate(97966-31-9)

Safety Data

• Hazardous Substances Data: 97966-31-9(Hazardous Substances Data)

Upstream product

• 2651-55-0 3-ethoxy-4-methoxybenzoic acid 
• 6702-50-7 3-hydroxy-4-methoxybenzoate 
• 75-03-6 ethyl iodide 
• 645-08-9 Isovanillic acid 
• 100-39-0 benzyl bromide 
• 617-05-0 ethyl vanillate 
• 6482-24-2 2-Bromoethyl methyl ether 
• 74-96-4 ethyl bromide 
• 121-34-6 3-methoxy-4-hydroxybenzoic acid 

Downstream Products

• 214470-85-6 2-amino-5-ethoxy-4-methoxybenzoic acid methyl ester 
• 214470-75-4 4-chloro-6-ethoxy-7-methoxyquinoline-3-carbonitrile 
• 214470-78-7 6-ethoxy-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carbonitrile 
• 1026844-87-0 2-(dimethylamino-methyleneamino)-5-ethoxy-4-methoxy-benzoic acid methyl ester 
• 214470-90-3 5-ethoxy-4-methoxy-2-nitrobenzoic acid methyl ester 
• 2651-55-0 3-ethoxy-4-methoxybenzoic acid 

Relevant articles and documents

Method for synthesizing 1-(3-ethyoxyl-4-methoxy)phenyl-2-methyl-sulfonyl ethylamine

The invention discloses a method for synthesizing 1-(3-ethyoxyl-4-methoxy)phenyl-2-methyl-sulfonyl ethylamine and belongs to the technical field of organic synthesis processes. The method comprises the following steps: taking 3-hydroxy-4-methoxybenzoic acid as a raw material, carrying out an esterification reaction to obtain 3-hydroxy-4-methoxybenzoate, reacting with bromoethane to obtain 3-ethyoxyl-4-methoxybenzoate, then reacting with dimethyl sulfone to obtain 1-(3-ethyoxyl-4-methoxy)phenyl-2-methyl sulfonyl ethyl ketone, and finally carrying out a reductive amination reaction with ammoniumformate, thereby obtaining the 1-(3-ethyoxyl-4-methoxy)phenyl-2-methyl-sulfonyl ethylamine.

USE OF CYANOQUINOLINES FOR TREATING OR INHIBITING COLONIC POLYPS

This invention provides a method of treating or inhibiting colonic polyps which comprises providing a compound of formula (1); wherein R1, R2, R3, R4, X, Y, and n are defined hereinbefore, or a pharmaceutically acceptable salt thereof.

SUBSTITUTED 3-CYANO QUINOLINES

This invention provides compounds having formula (1), wherein: X is cycloalkyl which may be optionally substituted; or is a pyridinyl, pyrimidinyl, or phenyl ring; wherein the pyridinyl, pyrimidinyl, or phenyl ring may be optionally substituted; n is 0-1; Y is -NH-, -O-, -S-, or -NR-; R is alkyl of 1-6 carbon atoms; R1, R2, R3 and R4 are each, independently, hydrogen, halogen, alkyl, alkenyl, alkynyl, alkenyloxy, alkynyloxy, hydroxymethyl, halomethyl, alkanoyloxy, alkenoyloxy, alkynoyloxy, alkanoyloxymethyl, alkenoyloxymethyl, alkynoyloxymethyl, alkoxymethyl, alkoxy, alkylthio, alkylsulphinyl, alkylsulphonyl, alkylsulfonamido, alkenylsulfonamido, alkynylsulfonamido, hydroxy, trifluoromethyl, cyano, nitro, carboxy, carboalkoxy, carboalkyl, phenoxy, phenyl, thiophenoxy, benzyl, amino, hydroxyamino, alkoxyamino, alkylamino, dialkylamino, aminoalkyl, N-alkylaminoalkyl, N,N-dialkylaminoalkyl, phenylamino, benzylamino, formulae (a, b, c, d, e, f, g, h, i, j, k, l, m, n, o, p, q or r); R5 is alkyl which may be optionally substituted, or phenyl which may be optionally substituted; R6 is hydrogen, alkyl, or alkenyl; R7 is chloro or bromo; R8 is hydrogen, alkyl, aminoalkyl, N-alkylaminoalkyl, N,N-dialkylaminoalkyl, N-cycloalkylaminoalkyl, N-cycloalkyl-N-alkylaminoalkyl, N,N-dicycloalkylaminoalkyl, morpholino-N-alkyl, piperidino-N-alkyl, N-alkyl-piperidino-N-alkyl, azacycloalkyl-N-alkyl, hydroxyalkyl, alkoxyalkyl, carboxy, carboalkoxy, phenyl, carboalkyl +, chloro, fluoro, or bromo; Z is amino, hydroxy, alkoxy, alkylamino, dialkylamino, morpholino, piperazino, N-alkylpiperazino, or pyrrolidino; m = 1-4, q = 1-3, and p = 0-3; any of the substituents R1, R2, R3 or R4 that are located on contiguous carbon atoms can together be the divalent radical -O-C(R8)2-O-; or a pharmaceutically acceptable salt thereof with the proviso that when Y is -NH-, R1, R2, R3 and R4 are hydrogen, and n is O, X is not 2-methylphenyl, which are inhibitors of protein tyrosine kinase.