98102-90-0

Basic information

• Product Name: (-) Cis 2-isopropyl cyclohexanol
• Synonyms: (-) Cis 2-isopropyl cyclohexanol
• CAS NO: 98102-90-0
• Molecular Weight: 142.241
• Mol File: 98102-90-0.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: (-) Cis 2-isopropyl cyclohexanol(CAS DataBase Reference)
• NIST Chemistry Reference: (-) Cis 2-isopropyl cyclohexanol(98102-90-0)
• EPA Substance Registry System: (-) Cis 2-isopropyl cyclohexanol(98102-90-0)

Safety Data

• Hazardous Substances Data: 98102-90-0(Hazardous Substances Data)

Upstream product

• 1004-77-9 2-isopropylcyclohexanone 
• 555-31-7 aluminum isopropoxide 
• 88-69-7 2-(1-methylethyl)phenol 
• 286-20-4 cyclohexane-1,2-epoxide 
• 75-26-3 isopropyl bromide 
• 822-87-7 2-Chlorocyclohexanone 
• 696-29-7 (1-methylethyl)-cyclohexane 
• 10488-25-2 cis-2-isopropylcyclohexan-1-ol 
• 67-63-0 isopropyl alcohol 
• 67-64-1 acetone 
• 64-17-5 ethanol 
• 64-19-7 acetic acid 

Downstream Products

• 10488-25-2 cis-2-isopropylcyclohexan-1-ol 
• 98102-89-7 (-) Trans 2-isopropyl cyclohexanol 
• 1975-32-2 (R)-2-isopropylcyclohexanone 
• 98102-91-1 (R)(+)-1r-Isopropyl-cyclohexanol-(2t) 

Relevant articles and documents

Asymmetric Induction via a Helically Chiral Anion: Enantioselective Pentacarboxycyclopentadiene Br?nsted Acid-Catalyzed Inverse-Electron-Demand Diels-Alder Cycloaddition of Oxocarbenium Ions

An enantioselective catalytic inverse-electron-demand Diels-Alder reaction of salicylaldehyde acetal-derived oxocarbenium ions and vinyl ethers to generate 2,4-dioxychromanes is described. Chiral pentacarboxycyclopentadiene (PCCP) acids are found to be effective for a variety of substrates. Computational and X-ray crystallographic analyses support the unique hypothesis that an anion with point-chirality-induced helical chirality dictates the absolute sense of stereochemistry in this reaction.

Synthesis of ruthenium-hydride complexes and preparation procedures of chiral alcohols and ketones

trans-RuH(η1-BH4)[(S)-xylbinap][(S,S)-dpen] (0.00125 mmol), acetophenone (5.0 mmol), and 2-propanol (2.5 mL) were placed in an autoclave, and the resulting solution was repeatedly subject 5 times to a procedure of performing pressure reduction and argon introduction while stirring the solution for deaeration. A hydrogen tank was then connected to the autoclave, and after replacing the air inside an introduction tube with hydrogen, the pressure inside the autoclave was adjusted to 5 atmospheres and then hydrogen was released until the pressure dropped to 1 atmosphere. After repeating this procedure 10 times, the hydrogen pressure was adjusted to 8 atmospheres and stirring at 25° C. was performed for 12 hours. By concentrating the solution obtained by depressurization and subjecting the crude product to simple distillation, (R)-1-phenylethanol (yield: 95%) in the form of a colorless oily substance was obtained at an ee of 99%.

Diastereoselective reduction of cyclohexanones with diisobutylaluminium phenoxides in terms of the isoinversion principle

The diastereoselectivity of the reduction of 2-substituted cyclohexanones 1-6 with 4-substituted diisobutylaluminium phenoxides a-d has been investigated as a function of temperature. The high-temperature region is found to be dominated by hydride transfer, which is controlled by steric as well as electronic effects. However, at low temperatures the Meerwein-Ponndorf-Verley reaction gains in Importance. This phenomenon is quantified by an isoinversion relationship.