982-57-0 Usage
Description
Chloramphenicol sodium succinate is a water-soluble derivative of chloramphenicol, a broad-spectrum antibiotic produced by the soil bacterium Streptomyces venezuelae. It exhibits a wide range of activity against both Gram-positive and Gram-negative bacteria, as well as antirickettsial properties. As a prodrug, chloramphenicol succinate is less active than chloramphenicol but is converted into the active form in the presence of succinate dehydrogenase.
Uses
Used in Pharmaceutical Industry:
Chloramphenicol sodium succinate is used as a broad-spectrum antibiotic for treating various bacterial infections. Its anti-bacterial and antirickettsial properties make it effective against a wide range of Gram-positive and Gram-negative bacteria.
Used in Drug Formulation:
Chloramphenicol succinate sodium is used as a pharmaceutical formulation to provide a more readily soluble product. The sodium salt form enhances the solubility of chloramphenicol, making it more suitable for administration and absorption in the body.
Used as a Prodrug:
Chloramphenicol succinate is used as a prodrug, which is significantly less active than chloramphenicol but is converted into the active form in the presence of succinate dehydrogenase. This conversion allows for the effective treatment of bacterial infections while minimizing potential side effects.
Air & Water Reactions
Freely soluble in water.
Fire Hazard
Flash point data for Chloramphenicol sodium succinate are not available, but Chloramphenicol sodium succinate is probably combustible.
Check Digit Verification of cas no
The CAS Registry Mumber 982-57-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 9,8 and 2 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 982-57:
(5*9)+(4*8)+(3*2)+(2*5)+(1*7)=100
100 % 10 = 0
So 982-57-0 is a valid CAS Registry Number.
InChI:InChI=1/C15H16Cl2N2O8.Na/c16-14(17)15(24)18-10(7-27-12(22)6-5-11(20)21)13(23)8-1-3-9(4-2-8)19(25)26;/h1-4,10,13-14,23H,5-7H2,(H,18,24)(H,20,21);/q;+1/p-1/t10-,13-;/m1./s1
