98534-80-6

Basic information

• Product Name: 2-(4-CHLOROPHENYL)-3-(TRIFLUOROMETHYL)PYRAZOLE-4-CARBOXYLIC ACID
• Synonyms: 1-(4-CHLOROPHENYL)-5-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID;2-(4-CHLOROPHENYL)-3-(TRIFLUOROMETHYL)PYRAZOLE-4-CARBOXYLIC ACID;BUTTPARK 47\18-26;TIMTEC-BB SBB001190;SALOR-INT L251372-1EA;2-(4-Chlorophenyl)-3-(trifluoromethyl)pyrazole-4-carboxylic acid 97%;2-(4-Chlorophenyl)-3-(trifluoromethyl)pyrazole-4-carboxylicacid97%;2-(4-Chlorophenyl)-3-(trifluoromethyl)pyrazole-4-
• CAS NO: 98534-80-6
• Molecular Formula: C₁₁H₆ClF₃N₂O₂
• Molecular Weight: 290.63
• EINECS: 200-589-5
• Mol File: 98534-80-6.mol
• Article Data: 6

Chemical Properties

• Melting Point: 137 °C
• Boiling Point: 368.9°C at 760 mmHg
• Flash Point: 176.9°C
• Appearance: /
• Density: 1.44g/cm³
• Vapor Pressure: 4.3E-06mmHg at 25°C
• Refractive Index: 1.557
• PKA: 2.71±0.36(Predicted)
• CAS DataBase Reference: 2-(4-CHLOROPHENYL)-3-(TRIFLUOROMETHYL)PYRAZOLE-4-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-CHLOROPHENYL)-3-(TRIFLUOROMETHYL)PYRAZOLE-4-CARBOXYLIC ACID(98534-80-6)
• EPA Substance Registry System: 2-(4-CHLOROPHENYL)-3-(TRIFLUOROMETHYL)PYRAZOLE-4-CARBOXYLIC ACID(98534-80-6)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 98534-80-6(Hazardous Substances Data)

Usage

General Description

2-(4-Chlorophenyl)-3-(trifluoromethyl)pyrazole-4-carboxylic acid is a chemical compound that belongs to the class of pyrazole carboxylic acids. It is a white to off-white crystalline powder with a molecular formula C11H6ClF3N2O2. 2-(4-CHLOROPHENYL)-3-(TRIFLUOROMETHYL)PYRAZOLE-4-CARBOXYLIC ACID is used in various fields such as pharmaceuticals, agrochemicals, and materials science. It has properties that make it suitable for use as an intermediate in the synthesis of active pharmaceutical ingredients and agrochemicals. Additionally, it has potential applications in the development of new materials and compounds. Its chemical structure and properties make it a valuable tool for medicinal and chemical research.

InChI:InChI=1/C11H7F3N2O2/c12-11(13,14)9-8(10(17)18)6-15-16(9)7-4-2-1-3-5-7/h1-6H,(H,17,18)

Upstream product

• 112055-36-4 1-(4-Chloro-phenyl)-5-trifluoromethyl-1H-pyrazole-4-carboxylic acid ethyl ester 
• 1073-70-7 4-chlorophenylhydrazine hydrochloride 
• 142503-29-5 3-dimethylaminomethylene-1,1,1,5,5,5-hexafluoropentane-2,4-dione 
• 1073-69-4 N-4-chlorophenylhydrazine 

Downstream Products

• 98534-25-9 1-(4-chlorophenyl)-N-methyl-5-(trifluoromethyl)-1H-4-carboxamide 
• 175137-19-6 1-(4-chloro-phenyl)-5-trifluoromethyl-1H-pyrazole-4-carbonyl chloride 
• 1083418-31-8 1-(4-chloro-phenyl)-5-trifluoromethyl-1H-pyrazole-4-carboxylic acid [5-chloro-2-(1H-tetrazol-5-yl)-phenyl]-amide 
• 1292281-84-5 C₃₀H₂₅ClF₃N₇O₃ 

Relevant articles and documents

Synthesis, Biological Evaluation, and 3D-QSAR Studies of N-(Substituted pyridine-4-yl)-1-(substituted phenyl)-5-trifluoromethyl-1 H-pyrazole-4-carboxamide Derivatives as Potential Succinate Dehydrogenase Inhibitors

A series of new fungicides that can inhibit the succinate dehydrogenase (SDH) was classified and named as SDH inhibitors by the Fungicide Resistance Action Committee in 2009. To develop more potential SDH inhibitors, we designed and synthesized a novel se

AMIDOPYRIDINE DERIVATIVE, AND USE THEREOF

The present invention relates to novel amidopyridine derivatives. More specifically, the present invention provides a medicinal agent which is useful as a prophylactic or therapeutic agent for diseases based on the production of cytokines from T cells, comprising as the active ingredient an amidopyridine derivative or a pharmacologically acceptable salt thereof. Provided are an amidopyridine derivative of the following general formula (I): wherein each symbol has the same meaning as defined in the description, or a pharmacologically acceptable salt thereof.

Pyrazole-amides and sulfonamides as sodium channel modulators

Compounds of the present invention modulate PN3 in mammals and are useful in treating pain in mammals.