98648-23-8

Basic information

• Product Name: 4'-Nitro-[1,1'-biphenyl]-4-carboxaldehyde
• Synonyms: 4'-NITRO[1,1'-BIPHENYL]-4-CARBALDEHYDE;4'-Nitro-[1,1'-biphenyl]-4-carboxaldehyde;4-(4-Nitrophenyl)benzaldehyde;4-Formyl-4'-nitrobiphenyl, 4-(4-Nitrophenyl)benzaldehyde;4'-Nitrobiphenyl-4-carboxaldehyde
• CAS NO: 98648-23-8
• Molecular Formula: C₁₃H₉NO₃
• Molecular Weight: 227.22
• Mol File: 98648-23-8.mol
• Article Data: 4

Chemical Properties

• Melting Point: 117-120°C
• Boiling Point: 404.9 °C at 760 mmHg
• Flash Point: 200.6 °C
• Appearance: /
• Density: 1.274 g/cm³
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 4'-Nitro-[1,1'-biphenyl]-4-carboxaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-Nitro-[1,1'-biphenyl]-4-carboxaldehyde(98648-23-8)
• EPA Substance Registry System: 4'-Nitro-[1,1'-biphenyl]-4-carboxaldehyde(98648-23-8)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 98648-23-8(Hazardous Substances Data)

Usage

General Description

4'-Nitro-[1,1'-biphenyl]-4-carboxaldehyde is a chemical compound that belongs to the category of nitrobenzene. It is a yellow solid with the molecular formula C13H9NO3, and it is primarily used as an intermediate in chemical synthesis. 4'-Nitro-[1,1'-biphenyl]-4-carboxaldehyde is commonly found in various research and industrial applications, including pharmaceuticals, dyes, and pigments. It is also used in organic synthesis to introduce the 4'-nitro-[1,1'-biphenyl]-4-carboxaldehyde group into different molecules. However, it is important to handle this chemical with care, as it can be toxic, irritating to the skin, eyes, and respiratory system, and may cause allergic skin reactions.

Upstream product

• 2143-88-6 4-nitro-4'-methyl-1,1'-biphenyl 
• 87199-17-5 4-formylphenylboronic acid, 
• 100-00-5 4-chlorobenzonitrile 
• 4482-01-3 o-benzenedisulfonimide 
• 100-01-6 4-nitro-aniline 

Downstream Products

• 98629-81-3 5,5'-<4'-nitro-1,1'-biphenyl>-4-ylmethylenebis(6-methylaminouracil) 
• 98629-74-4 5,5'-<4'-nitro-1,1'-biphenyl>-4-ylmethylenebis(6-methylamino-3-methyluracil) 
• 98629-77-7 8-p-aminophenyl-3,10-dimethylpyrimido<4,5-b>quinoline-2,4(3H,10H)-dione 
• 98629-76-6 8-p-nitrophenyl-3,10-dimethylpyrimido<4,5-b>quinoline-2,4(3H,10H)-dione 
• 98629-78-8 8--3,10-dimethylpyrimido<4,5-b>quinoline-2,4(3H,10H)-dione 
• 1268280-19-8 2-(4'-nitrobiphenyl)-4,5-bis[4-(N,N-dimethylamino)phenyl]-1H-imidazole 
• 1380049-04-6 (S)-2-{(R)-hydroxy[4'-nitro-1,1'-biphenyl-4-yl]methyl}cyclopentanone 

Relevant articles and documents

Easily synthesizable benzothiazole based designers palladium complexes for catalysis of Suzuki coupling: Controlling effect of aryl substituent of ligand on role and composition of insitu generated binary nanomaterial (PdS or Pd16S7)

The present report is based on straightforward synthesis of molecular palladium complexes of benzothiazole based bulky ligands. Catalytic potential of 1[Pd(L1)2Cl2] and 2[Pd(L2)2Cl2] has been screened for Suzuki coupling. Due to structural difference between 1 and 2 (anthracen-9-yl in 1, and pyren-1-yl in 2), they behave as designers pre-catalysts and show different catalytic behaviour and nature by dispensing the nanoparticles of different materials (PdS by 1 and Pd16S7 by 2). This is an unprecedented observation as the size of the aryl substituent controls the efficiency (efficiency: 1 > 2) through determining the composition and nature of insitu generated nanoparticles.

Sterically hindered N-aryl/benzyl substituted piperidoimidazolin-2-ylidene palladium complexes and their catalytic activities

A series of N-aryl (2a,b) or benzyl (2c,d) substituted piperidoimidazolinium salts and their palladium complexes (3a-d) were prepared and characterized by 1H, 13C NMR, IR spectroscopy and elemental analysis. The crystal structures of 3a and 3c have been determined by X-ray crystallography. Thermogravimetric analysis (TGA) was applied to complexes (3a–d). The palladium complexes have been employed as catalyst for Suzuki-Miyaura cross coupling. The N-aryl substituted complex 3b was a highly efficient precatalyst and successfully employed in Suzuki-Miyaura cross coupling reactions of (hetero)aryl chlorides with arylboronic acids in air. In addition, the oxidative addition step of the reaction mechanism involving chlorobenzene and the catalysts 3a, 3b, 3c and 3d were computationally investigated by the DFT-ω-B97X-D method and complete agreement were obtained with the catalytic results. To measure σ-donating and π-acceptor properties of the new ligands, the rhodium carbonyl complexes were also prepared.