98688-14-3

Basic information

• Product Name: N-<3-(benzyloxy)-4-methyl-2-nitrobenzoyl>-O-(tert-butoxycarbonyl-N-methyl-L-valyl)-L-threonyl-D-valyl-L-prolylsarcosine ter-butyl ester
• Synonyms: N-<3-(benzyloxy)-4-methyl-2-nitrobenzoyl>-O-(tert-butoxycarbonyl-N-methyl-L-valyl)-L-threonyl-D-valyl-L-prolylsarcosine ter-butyl ester
• CAS NO: 98688-14-3
• Molecular Weight: 925.089
• Mol File: 98688-14-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-<3-(benzyloxy)-4-methyl-2-nitrobenzoyl>-O-(tert-butoxycarbonyl-N-methyl-L-valyl)-L-threonyl-D-valyl-L-prolylsarcosine ter-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-<3-(benzyloxy)-4-methyl-2-nitrobenzoyl>-O-(tert-butoxycarbonyl-N-methyl-L-valyl)-L-threonyl-D-valyl-L-prolylsarcosine ter-butyl ester(98688-14-3)
• EPA Substance Registry System: N-<3-(benzyloxy)-4-methyl-2-nitrobenzoyl>-O-(tert-butoxycarbonyl-N-methyl-L-valyl)-L-threonyl-D-valyl-L-prolylsarcosine ter-butyl ester(98688-14-3)

Safety Data

• Hazardous Substances Data: 98688-14-3(Hazardous Substances Data)

Upstream product

• 27483-27-8 N-(benzyloxycarbonyl)-D-valylprolylsarcosine tert-butyl ester 
• 5616-83-1 H-D-Val-Pro-Sar-OBu^t 
• 2441-62-5 <3-(benzyloxy)-4-methyl-2-nitro-benzoyl>-L-threonine 

Downstream Products

• 2478-48-0 <3-(benzyloxy)-4-methyl-2-nitrobenzoyl>-L-threonyl-D-valyl-L-prolyl-sarcosyl-N-methyl-L-valine lactone 
• 21148-64-1 (3-hydroxy-4-methyl-2-nitrobenzoyl)-L-threonyl-D-valyl-L-prolyl-sarcosyl-N-methyl-L-valine lactone 
• 50-76-0 actinomycin D 
• 98757-23-4 (S)-2-(tert-Butoxycarbonyl-methyl-amino)-3-methyl-butyric acid (1R,2S)-2-(3-benzyloxy-4-methyl-2-nitro-benzoylamino)-2-{(R)-1-[(S)-2-(carboxymethyl-methyl-carbamoyl)-pyrrolidine-1-carbonyl]-2-methyl-propylcarbamoyl}-1-methyl-ethyl ester 

Relevant articles and documents

Conformation and Dimerization of Actinomycin-Related Peptide Lactones in Solution and in the Solid State

Actinomycin-related peptide lactone derivatives with the amino acid sequences Thr-D-Val-Pro-Sar-MeVal and Thr-D-Val-Pro-Sar-MeAla and the corresponding actinomycins (actinomycin D and its novel 5,5'-MeAla analoque) were synthesized by a new route.The solution properties of these compounds were studied by proton NMR in chloroform and acetone solutions.In dry chloroform, two conformers, A and C, are found, the ratio of which was concentration-dependent and results from dimerization of the A conformer.An X-ray crystallographic investigation of a Thr-D-Val-Pro-Sar-MeAla derivative indicated that hydrogen-bond associated pairs of A conformers, with a juxtapositional geometry remarkably similar to that known for actinomycin, were present in the solid state.