98856-64-5

Basic information

• Product Name: 3-Cyclohexene-1-carboxylicacid,6-amino-,(1S,6R)-(9CI)
• Synonyms: 3-Cyclohexene-1-carboxylicacid,6-amino-,(1S,6R)-(9CI)
• CAS NO: 98856-64-5
• Molecular Formula: C₇H₁₁NO₂
• Molecular Weight: 0
• Product Categories: AMINOACID
• Mol File: 98856-64-5.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Cyclohexene-1-carboxylicacid,6-amino-,(1S,6R)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Cyclohexene-1-carboxylicacid,6-amino-,(1S,6R)-(9CI)(98856-64-5)
• EPA Substance Registry System: 3-Cyclohexene-1-carboxylicacid,6-amino-,(1S,6R)-(9CI)(98856-64-5)

Safety Data

• Hazardous Substances Data: 98856-64-5(Hazardous Substances Data)

Upstream product

• 1469-49-4 6-carbamoylcyclohex-3-enecarboxylic acid 
• 85-40-5 1,2,3,6-tertahydrophthalimide 
• 1469-49-4 trans-2-Carboxamidocyclohex-4-enecarboxylic acid 
• 109577-02-8 methyl (1S,2R)-2-<(2-methylsulfonyl)ethoxycarbonylamino>-1-cyclohex-4-ene carboxylate 
• 98811-00-8 tert-butyl(1S,2R)-2-<(2-methylsulfonyl)ethoxycarbonylamino>-1-ciclohex-4-ene carboxylate 
• 102508-02-1 (1S,6R)-6-benzyloxycarbonylaminocyclohex-3-enecarboxylic acid 
• 285560-94-3 (1S,6R)-7-hydroxymethyl-7-azabicyclo[4.2.0]oct-3-en-8-one 
• 20205-48-5 8-oxo-7-azabicyclo<4.2.0>oct-2-ene 
• 31139-02-3 (1S,2R)-2-(methoxycarbonyl)cyclohex-4-ene-1-carboxylic acid 
• 93603-11-3 1-methyl hydrogen 1,2-cis-1,2-cyclohex-4-ene dicarboxylate 
• 31139-02-3 (1R,6S)-6-methoxycarbonyl-3-cyclohexene-1-carboxylic acid 
• 91259-92-6 (1S,2R)-Cyclohex-4-ene-1,2-dicarboxylic acid mono-tert-butyl ester 
• 98856-62-3 (1R,2S)-Cyclohex-4-ene-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester 
• 4841-84-3 dimethyl cis-1,2,3,6-tetrahydrophthalate 

Downstream Products

• 128349-75-7 cis-1,4,4a,6,7,8,9,11a-octahydropyrido<2,1-b>quinazolin-11-one 
• 128349-75-7 trans-1,4,4a,6,7,8,9,11a-octahydropyrido<2,1-b>quinazolin-11-one 
• 98769-56-3 cis-2-(hydroxymethyl)-4-cyclohexenyl-1-amine 
• 98769-56-3 trans-2-(hydroxymethyl)-4-cyclohexenyl-1-amine 
• 97945-17-0 (4aR,8aS)-3-Phenyl-2-thioxo-2,3,4a,5,8,8a-hexahydro-1H-quinazolin-4-one 
• 97945-17-0 (4aR,8aR)-3-Phenyl-2-thioxo-2,3,4a,5,8,8a-hexahydro-1H-quinazolin-4-one 
• 1226812-50-5 cis-2-(tert-butoxycarbonylamino)-4-cyclohexenecarboxylic acid 
• 1226812-50-5 trans-2-(tert-butoxycarbonylamino)-4-cyclohexenecarboxylic acid 
• 1226812-50-5 (1S,2R)-2-(tert-butoxycarbonylamino)-4-cyclohexenecarboxylic acid 
• 98769-61-0 cis-2-(p-clorophenyl)-1,2,4a,5,8,8a-hexahydro-4H-3,1-benzoxazine 

Relevant articles and documents

A convenient Hofmann reaction of carboxamides and cyclic imides mediated by trihaloisocyanuric acids

A simple, efficient and pot-economic approach in a single vessel has been developed for conversion of aromatic and aliphatic carboxamides into primary amines with one fewer carbom atom (Hofmann reaction) in 38–89 % yield by reacting with trichloro- or tribromoisocyanuric acid and sodium hydroxide in aqueous acetonitrile. Under the same reaction conditions, cyclic imides gave amino acids (69–83 %). The role of the trihaloisocyanuric acids is the in situ generation of N-haloamides, key-intermediates for the Hofmann reaction. The scalability of the methodology was demonstrated by a multigram-scale transformation of phthalimide into anthranilic acid in 77 % yield.

Synthesis of β-lactams bearing functionalized side chains from a readily available precursor

(Chemical Equation Presented) The reaction of chlorosulfonyl isocyanate (CSI) with alkenes provides β-lactams in quantity, and the products have frequently been used for ring-opening polymerization to generate nylon-3 materials. Prior uses of this approach have focused almost entirely on β-lactams with purely hydrocarbon substitutents. We show how a variety of β-lactams bearing protected polar substituents can be generated from CSI-derived building blocks.

Carbapenems, their production and use

A compound of the general formula: STR1 wherein X is a lower alkylene group which may optionally be substituted by a hydroxyl group, or a lower alkenylene group, Y is (1) a lower alkyl group, (2) a cycloalkyl group containing 3 to 8 carbon atoms, (3) a lower alkenyl group, (4) an aryl group, (5) an aralkyl group or (6) a 3- to 8-membered heterocyclic group, or the partial structural formula Y--SO2 --X--, with X and Y being combined with each other, represents a group of the formula: STR2 wherein l is an integer of 0 to 3, and m and n each is an integer of 0 to 6, provided that the sum of m and n is in the range of 2 to 6, and R is a hydrocarbon group which may optionally be substituted or a 3- to 8-membered heterocyclic group, or a pharmaceutically acceptable salt thereof a method of production thereof and use thereof. The compound (I) has antimicrobial and β-lactamase inhibitory activities.