98901-15-6

Basic information

• Product Name: N-tert-butyl-2-phenyl-2-o-tolylacetamide
• CAS NO: 98901-15-6
• Molecular Weight: 281.398
• Mol File: 98901-15-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-tert-butyl-2-phenyl-2-o-tolylacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-tert-butyl-2-phenyl-2-o-tolylacetamide(98901-15-6)
• EPA Substance Registry System: N-tert-butyl-2-phenyl-2-o-tolylacetamide(98901-15-6)

Safety Data

• Hazardous Substances Data: 98901-15-6(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 92548-88-4 2-phenyl-2-(o-tolyl)acetic acid 
• 98901-21-4 2-phenyl-2-(o-tolyl)acetonitrile 
• 5472-13-9 2-methylbenzhydrol 
• 41870-52-4 α-phenyl-o-methylbenzyl chloride 
• 932-31-0 ortho-tolylmagnesium bromide 
• 92435-45-5 Phenyl-o-tolyl-acetylchlorid 
• 75-64-9 tert-butylamine 
• 27151-60-6 1-t-butyl-3-phenylaziridin-2-one 
• 1589-82-8 phenylmagnesium bromide 

Relevant articles and documents

Reactions of 1-tert-Butyl-3-phenylaziridinone and α-Bromo-N-tert-butylphenylacetamide with Benzyl-Grignard Reagents

1-tert-Butyl-3-phenylaziridinone (1) reacts with benzyl halide Grignard reagents (Br and Cl) to give N-tert-butyl-2,3-diphenylpropanamide (4), N-tert-butyl-2-phenylacetamide (3), N-tert-butyl-2-o-tolyl-2-phenylacetamide (5), 1-(tert-butylamino)-1,3-diphenylpropan-2-one (7), N-benzyl-N-tert-butyl-2-phenylacetamide (6), and N-tert-butyl-2-halo-2-phenylacetamide (2, X = Br, Cl).The choice of solvent appears to determine the relative amounts of products 4 and 5.The bromo amide 2 reacts with the Grignard reagent to give 3, 4, 5, 6, and 7 and may be involved to some extentin the reaction of 1 with benzyl-Grignard reagents.The formation of 5 represents anew type of "abnormal" product from a reaction of the benzyl-Grignard reagent; however, this product appears to fit well into the mechanistic pattern established for prior examples.