99171-11-6

Basic information

• Product Name: Thiazole, 2-amino-5-(methylthio)- (6CI)
• Synonyms: Thiazole, 2-amino-5-(methylthio)- (6CI);5-(methylthio)thiazol-2-amine;Thiazole, 2-amino-5-(methylthio);2-Thiazolamine, 5-(methylthio)-;5-(Methylsulfanyl)-1,3-thiazol-2-aMine;2-AMino-5-(Methylthio)thiazole;5-(Methylthio)-2-thiazolamine;NSC 522650
• CAS NO: 99171-11-6
• Molecular Formula: C₄H₆N₂S₂
• Molecular Weight: 146.23
• EINECS: 921-254-7
• Product Categories: AMINEPRIMARY
• Mol File: 99171-11-6.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 303.5 °C at 760 mmHg
• Flash Point: 137.4 °C
• Appearance: /
• Density: 1.37 g/cm³
• Vapor Pressure: 0.000927mmHg at 25°C
• Refractive Index: 1.652
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: Thiazole, 2-amino-5-(methylthio)- (6CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Thiazole, 2-amino-5-(methylthio)- (6CI)(99171-11-6)
• EPA Substance Registry System: Thiazole, 2-amino-5-(methylthio)- (6CI)(99171-11-6)

Safety Data

• Hazardous Substances Data: 99171-11-6(Hazardous Substances Data)

Usage

General Description

Thiazole, 2-amino-5-(methylthio)- (6CI) is a chemical compound with the molecular formula C4H6N2S. It is a thiazole derivative with a 2-amino-5-(methylthio) substituent. Thiazoles are heterocyclic compounds containing a five-membered ring with sulfur and nitrogen atoms. This particular compound is used in various industrial applications, including as a building block in organic synthesis and as a reagent in pharmaceutical research. It is also used in the production of agrochemicals and dyes. The compound's properties and structure make it suitable for use in a range of chemical processes and industries.

InChI:InChI=1/C4H6N2S2/c1-7-3-2-6-4(5)8-3/h2H,1H3,(H2,5,6)

Upstream product

• 36016-97-4 2-acetamino-5-thiocyanatothiazole 
• 96-50-4 2-thiazolylamine 
• 624-92-0 Dimethyldisulphide 
• 1109286-15-8 C₅H₁₁BrO₂S 
• 17356-08-0 thiourea 
• 61296-22-8 5-bromothiazol-2-amine hydrobromide 
• 5188-07-8 sodium thiomethoxide 
• 1228461-89-9 C₉H₁₄N₂O₂S₂ 
• 3034-22-8 5-bromo-2-aminothiazole 

Downstream Products

• 69949-95-7 (6-methanesulfinyl-thiazolo[2,3-c][1,2,4]thiadiazol-3-ylidene)-phenyl-amine 
• 1109286-02-3 2-(5-(methylthio)thiazol-2-ylcarbamoyl)phenyl acetate 
• 1208552-97-9 C₁₆H₁₉ClN₂OS₂ 

Relevant articles and documents

SUBSTITUTED PYRROLOPYRIDINES AS JAK INHIBITORS

The present invention relates to new pyrrolopyridine compounds having the structures of Formula (I)-(IV), wherein the R groups, A, B, C, D and n are as defined in the detailed description, and compositions and their application as pharmaceuticals for the treatment of disease. Methods of inhibition of JAK kinase activity in a human or animal subject are also provided for the treatment diseases such as pruritus, alopecia, androgenetic alopecia, alopecia areata, vitiligo and psoriasis.

ALKYLSULFINYL-SUBSTITUTED THIAZOLIDE COMPOUNDS

A new class of alkylsulfinyl thiazolides is described. These compounds show strong activity against hepatitis viruses

Sulfonylureido thiazoles as fructose-1,6-bisphosphatase inhibitors for the treatment of Type-2 diabetes

Sulfonylureido thiazoles were identified from a HTS campaign and optimized through a combination of structure-activity studies, X-ray crystallography and molecular modeling to yield potent inhibitors of fructose-1,6-bisphosphatase. Compound 12 showed favo