99632-51-6Relevant articles and documents
Investigation of the 2,5-Dimethoxy Motif in Phenethylamine Serotonin 2A Receptor Agonists
Chatha, Muhammad,Halberstadt, Adam L.,Jademyr, Simon,Jensen, Anders A.,Klein, Adam K.,Kristensen, Jesper L.,Marcher-R?rsted, Emil
, p. 1238 - 1244 (2020/05/27)
The 2,5-dimethoxyphenethylamine (2,5-PEA) scaffold is recognized as a motif conferring potent agonist activity at the serotonin 2A receptor (5-HT2AR). The 2,5-dimethoxy motif is present in several classical phenethylamine psychedelics such as 2