Product Name

  • Name

    1-Acetyl-2-phenylhydrazine

  • EINECS 204-055-3
  • CAS No. 114-83-0
  • Article Data113
  • CAS DataBase
  • Density 1.143 g/cm3
  • Solubility insoluble in water
  • Melting Point 128-131 °C(lit.)
  • Formula C8H10N2O
  • Boiling Point 214.1 °C at 760 mmHg
  • Molecular Weight 150.18
  • Flash Point 87.8 °C
  • Transport Information UN 2811
  • Appearance colorless prisms or white solid
  • Safety 22-26-36-24/25
  • Risk Codes 22-36/37/38-43-20/21/22
  • Molecular Structure Molecular Structure of 114-83-0 (1-Acetyl-2-phenylhydrazine)
  • Hazard Symbols HarmfulXn
  • Synonyms N(1)-Acetylphenylhydrazine;1-Phenyl-2-acetylhydrazine;AI3-01560;APH;Acetic acid phenylhydrazone;Acetylphenylhydrazine;BRN 0742880;CCRIS 4569;Fenylhydrazid kyseliny octove;
  • PSA 41.13000
  • LogP 1.61350

Synthetic route

acetic anhydride
108-24-7

acetic anhydride

phenylhydrazine
100-63-0

phenylhydrazine

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

Conditions
ConditionsYield
In diethyl ether at 0℃; for 10h;100%
Stage #1: phenylhydrazine With triethylamine In dichloromethane at 0℃; Inert atmosphere;
Stage #2: acetic anhydride In dichloromethane at 0 - 20℃; Inert atmosphere;
97%
With pyridine; aluminum oxide at 90 - 92℃; for 1h; microwave irradiation;65%
1,1,1-trichloroacetone
918-00-3

1,1,1-trichloroacetone

phenylhydrazine
100-63-0

phenylhydrazine

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

Conditions
ConditionsYield
With triethylamine In acetonitrile for 8h; Heating;98%
acetic acid
64-19-7

acetic acid

phenylhydrazine
100-63-0

phenylhydrazine

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

Conditions
ConditionsYield
at 80℃; for 3.5h; Inert atmosphere;96%
at 80℃; for 1.5h;85%
at 20 - 80℃; for 1.5h; Inert atmosphere;81%
4-Acetamido-1-iodobenzene
622-50-4

4-Acetamido-1-iodobenzene

phenylhydrazine
100-63-0

phenylhydrazine

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

Conditions
ConditionsYield
at 95℃; for 2.5h; Temperature;93%
phenylhydrazine
100-63-0

phenylhydrazine

thioacetic acid
507-09-5

thioacetic acid

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

Conditions
ConditionsYield
With copper(II)-grafted guanidine acetic acid-modified magnetite nanoparticles In water at 20℃; for 0.0833333h; Green chemistry; chemoselective reaction;90%
With Fe3O4(at)Chit-TCT-Salen-Cu(II) In water at 20℃; for 0.0833333h; regioselective reaction;89%
phenylhydrazine hydrochloride
59-88-1

phenylhydrazine hydrochloride

acetic acid
64-19-7

acetic acid

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 20℃; Inert atmosphere;89%
phenylhydrazine hydrochloride
59-88-1

phenylhydrazine hydrochloride

acetic anhydride
108-24-7

acetic anhydride

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 24h;87%
With potassium carbonate In ethyl acetate at 20℃; for 7h; Inert atmosphere; regioselective reaction;82%
With sodium hydroxide In tetrahydrofuran for 0.5h; Inert atmosphere;
With sodium hydroxide In tetrahydrofuran for 0.5h;
phenylhydrazine
100-63-0

phenylhydrazine

acetone
67-64-1

acetone

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

Conditions
ConditionsYield
With chloroform; dimethyl sulfoxide at 120℃; for 24h; Green chemistry;84%
acetamide
60-35-5

acetamide

phenylhydrazine
100-63-0

phenylhydrazine

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

Conditions
ConditionsYield
With [bis(acetoxy)iodo]benzene In neat (no solvent) at 120℃; for 0.333333h; Microwave irradiation; Green chemistry;83%
In 1,4-dioxane at 20℃; for 0.5h; Microwave irradiation; Sealed tube;78%
With [Mn((N'1E,N'2E)-N'1,N'2-bis(phenyl(pyridin-2-yl)methylene)oxalohydrazide(-H))(OAc)(H2O)]2*6H2O In neat (no solvent) at 120℃; for 24h;70%
at 160℃; under 12929 Torr; for 0.166667h; Microwave irradiation; Sealed tube;54%
at 150℃;
benzenediazonium
2684-02-8

benzenediazonium

dimethylglyoxal
431-03-8

dimethylglyoxal

A

biacetyl phenylhydrazone
13732-32-6

biacetyl phenylhydrazone

B

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

Conditions
ConditionsYield
With titanium(III) chloride In acetic acid for 0.666667h; Ambient temperature;A 16%
B 65%
mono-O-acetyl maleic hydrazide
15456-83-4

mono-O-acetyl maleic hydrazide

phenylhydrazine
100-63-0

phenylhydrazine

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 70 - 80℃; for 2h;65%
phenylhydrazine
100-63-0

phenylhydrazine

ethyl 2-acetylacetoacetate
603-69-0

ethyl 2-acetylacetoacetate

A

3-methyl-2-pyrazoline-5-one
108-26-9

3-methyl-2-pyrazoline-5-one

B

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

Conditions
ConditionsYield
In diethyl ether at -30 - -25℃;A n/a
B 64%
2,5-dimethyl-2-phenylazo-furan-3-one
70638-40-3

2,5-dimethyl-2-phenylazo-furan-3-one

A

Acetic acid N-((Z)-3-amino-but-2-enoyl)-N'-phenyl-hydrazide
83326-39-0

Acetic acid N-((Z)-3-amino-but-2-enoyl)-N'-phenyl-hydrazide

B

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

Conditions
ConditionsYield
With ammonia In methanol 1.) 0 deg C, 15 min, 2.) RT; Yield given;A 60%
B n/a
With ammonia In methanol 1.) 0 deg C, 15 min, 2.) RT; Yields of byproduct given;A 60%
B n/a
benzene-1,2-diol
120-80-9

benzene-1,2-diol

2-(diethylamino)-5-methyl-3-phenyl-2-(phenylimino)-Δ4-1,3,4,2λ5-oxadiazaphospholine
99049-24-8

2-(diethylamino)-5-methyl-3-phenyl-2-(phenylimino)-Δ4-1,3,4,2λ5-oxadiazaphospholine

A

diethylammonium tris(o-phenylenedioxy)phosphate

diethylammonium tris(o-phenylenedioxy)phosphate

B

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

Conditions
ConditionsYield
In chloroform for 0.5h; Heating;A 53%
B n/a
benzene-1,2-diol
120-80-9

benzene-1,2-diol

N-cyclohexyl-N'-phenylphosphorodiamidic 2-acetyl-1-phenylhydrazide
99049-28-2

N-cyclohexyl-N'-phenylphosphorodiamidic 2-acetyl-1-phenylhydrazide

A

cyclohexylammonium tris(o-phenylenedioxy)phosphate

cyclohexylammonium tris(o-phenylenedioxy)phosphate

B

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

Conditions
ConditionsYield
In chloroform for 0.5h; Heating;A 41%
B n/a
benzenediazonium
2684-02-8

benzenediazonium

1-Phenylpropane-1,2-dione
579-07-7

1-Phenylpropane-1,2-dione

A

1-phenyl-propane-1,2-dione-2-phenylhydrazone
20999-77-3

1-phenyl-propane-1,2-dione-2-phenylhydrazone

B

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

C

N-benzoyl-N'-phenylhydrazine
532-96-7

N-benzoyl-N'-phenylhydrazine

Conditions
ConditionsYield
With titanium(III) chloride In acetic acid at 50℃; for 0.666667h;A 29%
B 25%
C 40%
phenylhydrazine
100-63-0

phenylhydrazine

4-acetyl-3-amino-5-oxo-3-hexenenitrile
106823-51-2

4-acetyl-3-amino-5-oxo-3-hexenenitrile

A

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

B

(Z)-3-Amino-5-oxo-hex-3-enenitrile

(Z)-3-Amino-5-oxo-hex-3-enenitrile

C

5-cyanomethylene-3-methyl-1-phenylpyrazole

5-cyanomethylene-3-methyl-1-phenylpyrazole

Conditions
ConditionsYield
In ethanol for 72h; Ambient temperature;A 40%
B 24%
C 18%
benzenediazonium
2684-02-8

benzenediazonium

1-Phenylpropane-1,2-dione
579-07-7

1-Phenylpropane-1,2-dione

A

1-phenyl-propane-1,2-dione-2-phenylhydrazone
20999-77-3

1-phenyl-propane-1,2-dione-2-phenylhydrazone

B

1-acetyl-1-benzoyl-2-phenylhydrazine
136953-46-3

1-acetyl-1-benzoyl-2-phenylhydrazine

C

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

D

N-benzoyl-N'-phenylhydrazine
532-96-7

N-benzoyl-N'-phenylhydrazine

Conditions
ConditionsYield
With titanium(III) chloride In acetic acid for 0.666667h;A 28%
B 35%
C 10%
D 22%
acetyl-methyl-malonic acid diethyl ester
28286-72-8

acetyl-methyl-malonic acid diethyl ester

phenylhydrazine acetate
72358-76-0

phenylhydrazine acetate

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

(1-nitro-ethylidene)-phenyl-hydrazine
20604-81-3

(1-nitro-ethylidene)-phenyl-hydrazine

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

Conditions
ConditionsYield
With sodium methylate
N'-acetyl-N-formyl-N-phenylhydrazine

N'-acetyl-N-formyl-N-phenylhydrazine

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

Conditions
ConditionsYield
With sodium carbonate
acetic anhydride
108-24-7

acetic anhydride

acetone phenylhydrazone
103-02-6

acetone phenylhydrazone

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

Conditions
ConditionsYield
With acetone
acetic anhydride
108-24-7

acetic anhydride

acetone phenylhydrazone
103-02-6

acetone phenylhydrazone

A

N'-acetyl-N'-phenylacetohydrazide
38604-74-9

N'-acetyl-N'-phenylacetohydrazide

B

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

phenyl-hydrazine; sodium-compound
59105-56-5

phenyl-hydrazine; sodium-compound

acetic anhydride
108-24-7

acetic anhydride

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

diethyl ether
60-29-7

diethyl ether

acetic anhydride
108-24-7

acetic anhydride

phenylhydrazine
100-63-0

phenylhydrazine

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

Conditions
ConditionsYield
bei der Einwirkung auf Phenylhydrazinnatrium;
acetic anhydride
108-24-7

acetic anhydride

phenylhydrazine
100-63-0

phenylhydrazine

benzene
71-43-2

benzene

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

phenylhydrazine acetate
72358-76-0

phenylhydrazine acetate

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

Conditions
ConditionsYield
at 80 - 90℃;
Acetyl cyanide
631-57-2

Acetyl cyanide

propionic acid
802294-64-0

propionic acid

phenylhydrazine
100-63-0

phenylhydrazine

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

ethyl acetate
141-78-6

ethyl acetate

phenylhydrazine
100-63-0

phenylhydrazine

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

Conditions
ConditionsYield
at 170℃; im Druckrohr;
phenyl-hydrazine; sodium-compound
59105-56-5

phenyl-hydrazine; sodium-compound

acetyl chloride
75-36-5

acetyl chloride

A

N'-acetyl-N'-phenylacetohydrazide
38604-74-9

N'-acetyl-N'-phenylacetohydrazide

B

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

chloroacetyl chloride
79-04-9

chloroacetyl chloride

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

2-acetyl-1-(2-chloroacetyl)phenylhydrazine
108511-46-2

2-acetyl-1-(2-chloroacetyl)phenylhydrazine

Conditions
ConditionsYield
In dichloromethane for 0.5h;100%
With benzene
acetic anhydride
108-24-7

acetic anhydride

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

N'-acetyl-N'-phenylacetohydrazide
38604-74-9

N'-acetyl-N'-phenylacetohydrazide

Conditions
ConditionsYield
99%
trimethyl(pentafluorophenyl)silane
1206-46-8

trimethyl(pentafluorophenyl)silane

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

A

Pentafluorobenzene
363-72-4

Pentafluorobenzene

B

trimethylsilyl acetate phenyl(trimethylsilyl)hydrazone

trimethylsilyl acetate phenyl(trimethylsilyl)hydrazone

Conditions
ConditionsYield
With (K-18-crown-6 ether) cyanide In acetonitrile at 20℃; for 8h; sealed evacuated ampul;A n/a
B 98%
1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

1-methyl-3-phenyl-2,3-diazaprop-2-en-1-one
13443-97-5

1-methyl-3-phenyl-2,3-diazaprop-2-en-1-one

Conditions
ConditionsYield
With pyridine; manganese(IV) oxide; bromine In dichloromethane at 0℃;98%
With pyridine; N-Bromosuccinimide In dichloromethane for 0.5h; Ambient temperature;79%
With potassium hexacyanoferrate(III) In sodium hydroxide; dichloromethane19%
iodobenzene
591-50-4

iodobenzene

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

1-acetyl-1,2-diphenylhydrazine
22293-38-5

1-acetyl-1,2-diphenylhydrazine

Conditions
ConditionsYield
With potassium phosphate; copper(l) iodide; 3-amino propanoic acid In 1,4-dioxane at 100℃; for 24h; Goldberg reaction;98%
Lawessons reagent
19172-47-5

Lawessons reagent

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

2-(4-Methoxy-phenyl)-5-methyl-3-phenyl-3H-[1,3,4,2]thiadiazaphosphole 2-sulfide
79201-96-0

2-(4-Methoxy-phenyl)-5-methyl-3-phenyl-3H-[1,3,4,2]thiadiazaphosphole 2-sulfide

Conditions
ConditionsYield
In benzene at 80℃; for 10h;97%
methyl 2-diazo-4-methoxy-3-oxobutanoate
105940-00-9

methyl 2-diazo-4-methoxy-3-oxobutanoate

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

methyl 1-acetamido-2-(methoxymethyl)-1H-indole-3-carboxylate
1610689-74-1

methyl 1-acetamido-2-(methoxymethyl)-1H-indole-3-carboxylate

Conditions
ConditionsYield
With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; cesium acetate; acetic acid In water at 100℃; for 0.5h; Inert atmosphere; Schlenk technique; Sealed tube;95%
1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

2-(dimethyl(oxo)-λ6-sulfaneylidene)-1-(furan-2-yl)ethan-1-one

2-(dimethyl(oxo)-λ6-sulfaneylidene)-1-(furan-2-yl)ethan-1-one

C14H12N2O2

C14H12N2O2

Conditions
ConditionsYield
With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; sodium acetate; acetic acid; silver(I) triflimide In 1,2-dichloro-ethane at 100℃; for 12h; Inert atmosphere;95%
trimethyl(pentafluorophenyl)silane
1206-46-8

trimethyl(pentafluorophenyl)silane

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

A

Pentafluorobenzene
363-72-4

Pentafluorobenzene

B

1-trimethylsiloxyethanone phenylhydrazone
92773-30-3

1-trimethylsiloxyethanone phenylhydrazone

Conditions
ConditionsYield
With (K-18-crown-6 ether) cyanide In acetonitrile at 20℃; for 1h; sealed evacuated ampul;A n/a
B 94%
1,2-bis(4-methylphenyl)acetylene
2789-88-0

1,2-bis(4-methylphenyl)acetylene

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

N-(2,3-di-p-tolyl-1H-indol-1-yl)acetamide

N-(2,3-di-p-tolyl-1H-indol-1-yl)acetamide

Conditions
ConditionsYield
With meta-dinitrobenzene; dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; sodium acetate In 1,2-dichloro-ethane at 60℃; Sealed tube; Inert atmosphere; Schlenk technique; regioselective reaction;94%
N-(4-methoxyphenyl)maleimide
1081-17-0

N-(4-methoxyphenyl)maleimide

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

N-(2-(4-methoxyphenyl)-1,3-dioxo-2,3-dihydropyrrolo[3,4-b]indol-4(1H)-yl)acetamide

N-(2-(4-methoxyphenyl)-1,3-dioxo-2,3-dihydropyrrolo[3,4-b]indol-4(1H)-yl)acetamide

Conditions
ConditionsYield
With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; silver carbonate; silver(I) triflimide In 1,2-dichloro-ethane at 90℃; for 6h; Inert atmosphere;94%
1,2-bis(4-methylphenyl)acetylene
2789-88-0

1,2-bis(4-methylphenyl)acetylene

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

2,3-bis(4-methylphenyl)-1H-indole

2,3-bis(4-methylphenyl)-1H-indole

Conditions
ConditionsYield
With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; cesium acetate; acetic acid In 1,2-dichloro-ethane at 70℃; for 16h; Inert atmosphere;93%
7-methylbenzofuran
17059-52-8

7-methylbenzofuran

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

7-methyl-2-phenylbenzofuran
50543-55-0

7-methyl-2-phenylbenzofuran

Conditions
ConditionsYield
With dichloro bis(acetonitrile) palladium(II); 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical In 1,4-dioxane at 100℃; for 24h; regioselective reaction;93%
2-(dimethyl(oxo)-λ6-sulfaneylidene)-1-phenylethan-1-one
20718-17-6

2-(dimethyl(oxo)-λ6-sulfaneylidene)-1-phenylethan-1-one

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

N-(2-phenyl-1H-indol-1-yl)acetamide

N-(2-phenyl-1H-indol-1-yl)acetamide

Conditions
ConditionsYield
With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; sodium acetate; acetic acid; silver(I) triflimide In 1,2-dichloro-ethane at 100℃; for 12h; Catalytic behavior; Reagent/catalyst; Solvent; Inert atmosphere;93%
With tris(acetonitrile)(η5-pentamethylcyclopentadienyl)rhodium(III) hexafluoroantimonate; zinc diacetate In 1,2-dichloro-ethane at 100℃; for 16h; Schlenk technique; Inert atmosphere;82%
With silver hexafluoroantimonate; dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; sodium acetate In tetrahydrofuran at 100℃; for 20h; Catalytic behavior; Reagent/catalyst; Solvent; Temperature; Inert atmosphere; Sealed tube;82%
2-(dimethyl(oxo)-λ6-sulfaneylidene)-1-(thiophen-2-yl)ethan-1-one

2-(dimethyl(oxo)-λ6-sulfaneylidene)-1-(thiophen-2-yl)ethan-1-one

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

N-(2-(thiophen-2-yl)-1H-indol-1-yl)acetamide

N-(2-(thiophen-2-yl)-1H-indol-1-yl)acetamide

Conditions
ConditionsYield
With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; sodium acetate; acetic acid; silver(I) triflimide In 1,2-dichloro-ethane at 100℃; for 12h; Inert atmosphere;93%
With silver hexafluoroantimonate; dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; sodium acetate In tetrahydrofuran at 100℃; for 20h; Inert atmosphere; Sealed tube;63%
1-(3-methylphenyl)-1H-pyrrole-2,5-dione
20299-79-0

1-(3-methylphenyl)-1H-pyrrole-2,5-dione

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

N-(1,3-dioxo-2-(m-tolyl)-2,3-dihydropyrrolo[3,4-b]indol-4(1H)-yl)acetamide

N-(1,3-dioxo-2-(m-tolyl)-2,3-dihydropyrrolo[3,4-b]indol-4(1H)-yl)acetamide

Conditions
ConditionsYield
With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; silver carbonate; silver(I) triflimide In 1,2-dichloro-ethane at 90℃; for 6h; Inert atmosphere;93%
diphenyl acetylene
501-65-5

diphenyl acetylene

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

N-(2,3-diphenyl-1H-indol-1-yl)acetamide

N-(2,3-diphenyl-1H-indol-1-yl)acetamide

Conditions
ConditionsYield
With meta-dinitrobenzene; dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; sodium acetate In 1,2-dichloro-ethane at 60℃; for 24h; Catalytic behavior; Reagent/catalyst; Solvent; Sealed tube; Inert atmosphere; Schlenk technique; regioselective reaction;92%
4,4'-dimethoxydiphenylacetylene
2132-62-9

4,4'-dimethoxydiphenylacetylene

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

indoxole
5034-76-4

indoxole

Conditions
ConditionsYield
With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; cesium acetate; acetic acid In 1,2-dichloro-ethane at 70℃; for 16h; Inert atmosphere;91%
1,2-bis(4-fluorophenyl)acetylene
5216-31-9

1,2-bis(4-fluorophenyl)acetylene

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

2,3-bis(4-fluorophenyl)-1H-indole
628320-79-6

2,3-bis(4-fluorophenyl)-1H-indole

Conditions
ConditionsYield
With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; cesium acetate; acetic acid In 1,2-dichloro-ethane at 70℃; for 16h; Inert atmosphere;91%
ethyl 2-diazo-3-oxobutanoate
2009-97-4

ethyl 2-diazo-3-oxobutanoate

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

ethyl 1-acetamido-2-methyl-1H-indole-3-carboxylate
1610689-50-3

ethyl 1-acetamido-2-methyl-1H-indole-3-carboxylate

Conditions
ConditionsYield
With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; cesium acetate; acetic acid In water at 100℃; for 1h; Reagent/catalyst; Concentration; Solvent; Time; Inert atmosphere; Schlenk technique; Sealed tube;91%
2-Diazo-3-oxo-butyric acid methyl ester
24762-04-7

2-Diazo-3-oxo-butyric acid methyl ester

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

methyl 1-acetamido-2-methyl-1H-indole-3-carboxylate
1610689-73-0

methyl 1-acetamido-2-methyl-1H-indole-3-carboxylate

Conditions
ConditionsYield
With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; cesium acetate; acetic acid In water at 100℃; for 1h; Inert atmosphere; Schlenk technique; Sealed tube;91%
5-methoxybenzofuran
13391-28-1

5-methoxybenzofuran

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

2-phenyl-5-methoxybenzo[b]furan
7182-32-3

2-phenyl-5-methoxybenzo[b]furan

Conditions
ConditionsYield
With dichloro bis(acetonitrile) palladium(II); 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical In 1,4-dioxane at 100℃; for 24h; regioselective reaction;91%
N-phenyl-maleimide
941-69-5

N-phenyl-maleimide

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

N-(1,3-dioxo-2-phenyl-2,3,3a,8b-tetrahydropyrrolo[3,4-b]indol-4(1H)-yl)acetamide

N-(1,3-dioxo-2-phenyl-2,3,3a,8b-tetrahydropyrrolo[3,4-b]indol-4(1H)-yl)acetamide

Conditions
ConditionsYield
With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; silver carbonate; silver(I) triflimide In 1,2-dichloro-ethane at 90℃; for 6h; Inert atmosphere;91%
1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

5-methyl-2-bromo-3-phenyl-2,3-dihydro-1,3,4,2-oxadiazaphosphole

5-methyl-2-bromo-3-phenyl-2,3-dihydro-1,3,4,2-oxadiazaphosphole

Conditions
ConditionsYield
With phosphorus pentabromide; triethylamine In benzene at 5 - 60℃; for 2h;90%
1-bromo-4-ethenyl-benzene
2039-82-9

1-bromo-4-ethenyl-benzene

1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

(E)-4-bromostilbene
13041-70-8

(E)-4-bromostilbene

Conditions
ConditionsYield
With copper(l) iodide; trifluoroacetic acid; palladium dichloride In dimethyl sulfoxide at 80℃;90%

1-Acetyl-2-phenylhydrazine Consensus Reports

Reported in EPA TSCA Inventory.

1-Acetyl-2-phenylhydrazine Specification

The Acetic acid, 2-phenylhydrazide, with the CAS registry number 114-83-0, is also known as 1-Acetyl-2-phenylhydrazine. Its molecular formula is C8H10N2O and its classification codes are Agricultural Chemical; Drug / Therapeutic Agent; Fungicide, bactericide, wood preservative; Mutation data; Tumor data. Additionally, it has the IUPAC name N'-phenylacetohydrazide. The product categories of this chemical are Aromatic Hydrazides, Hydrazines, Hydrazones and Oximes; Phenylhydrazine; Cancer Research; Carcinogens. Besides, it used as organic intermediates and stabilizer. Dry powder, foam, sand, carbon dioxide and water spray are made from this chemical which is soluble in water, ethanol and benzene. However, keep this chemical in the cool and dry place where there is no heat and oxides.

Other characteristics of the Acetic acid, 2-phenylhydrazide can be summarised as followings: (1)ACD/LogP: 0.84; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 0.84; (4)ACD/LogD (pH 7.4): 0.84; (5)ACD/BCF (pH 5.5): 2.58; (6)ACD/BCF (pH 7.4): 2.58; (7)ACD/KOC (pH 5.5): 68.51; (8)ACD/KOC (pH 7.4): 68.54; (9)#H bond acceptors: 3; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 2; (12)Polar Surface Area: 23.55 Å2; (13)Index of Refraction: 1.586; (14)Molar Refractivity: 44.11 cm3; (15)Molar Volume: 131.3 cm3; (16)Polarizability: 17.49×10-24cm3; (17)Surface Tension: 44.3 dyne/cm; (18)Density: 1.143 g/cm3; (19)Flash Point: 87.8 °C; (20)Enthalpy of Vaporization: 45.05 kJ/mol; (21)Boiling Point: 214.1 °C at 760 mmHg; (22)Vapour Pressure: 0.158 mmHg at 25°C.

Production method of this chemical: It could be obtained by the reactants of phenylhydrazine and acetic acid. This reaction shoudl be heated for 6h. Then cool the product below 0 °C and crude is filtered. Crystallization with water,  drying at 80 °C, the Acetic acid, 2-phenylhydrazide is derived.

Uses of the Acetic acid, 2-phenylhydrazide: It could react with propenal to obtain the 1-acetyl-5-hydroxy-2-phenylpyrazolidine. This reaction needs the solvent of diethyl ether. The yield is 74 %. In addition, this reaction should be taken for 20 minutes at the temperature of 20 °C. The type of this reaction is cyclization / condensation.

 the Acetic acid, 2-phenylhydrazide could react with propenal to obtain the 1-acetyl-5-hydroxy-2-phenylpyrazolidine

When you are using this chemical, please be cautious about it as the following: This chemical is irritating to eyes, respiratory system and skin. You should wear suitable protective clothing to avoid contacting with skin and eyes. In case of contacting with eyes, rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure: 
1.SMILES: O=C(NNc1ccccc1)C
2.InChI: InChI=1/C8H10N2O/c1-7(11)9-10-8-5-3-2-4-6-8/h2-6,10H,1H3,(H,9,11)
3.InChIKey: UICBCXONCUFSOI-UHFFFAOYAT

The toxicity data is as follows: 
 

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 oral 270mg/kg (270mg/kg)   Pharmaceutical Chemistry Journal Vol. 14, Pg. 162, 1980.
mouse LDLo intraperitoneal 150mg/kg (150mg/kg)   National Technical Information Service. Vol. AD691-490,

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